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Merge pull request #28370 from geneontology/issue-28327
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Added refs to ESC/E(Z) complex; #28327
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raymond91125 authored Jul 1, 2024
2 parents 760277e + 128347d commit 31233fc
Showing 1 changed file with 3 additions and 1 deletion.
4 changes: 3 additions & 1 deletion src/ontology/go-edit.obo
Original file line number Diff line number Diff line change
Expand Up @@ -210262,11 +210262,13 @@ relationship: part_of GO:0005654 ! nucleoplasm
id: GO:0035098
name: ESC/E(Z) complex
namespace: cellular_component
def: "A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4." [GOC:bf, GOC:sp, PMID:12408863, PMID:12408864, PMID:20064375]
def: "A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4." [GOC:bf, GOC:krc, GOC:sp, PMID:12408863, PMID:12408864, PMID:17107999, PMID:20064375, PMID:31123059, PMID:33232890]
synonym: "Extra Sex Combs/Enhancer of Zeste complex" EXACT []
synonym: "polycomb repressive complex 2" EXACT []
synonym: "PRC2 complex" EXACT [GOC:sp, PMID:20064375]
is_a: GO:0031519 ! PcG protein complex
is_a: GO:0035097 ! histone methyltransferase complex
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28327" xsd:anyURI

[Term]
id: GO:0035099
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