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Added refs to ESC/E(Z) complex; #28327
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raymond91105 committed Jul 1, 2024
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4 changes: 3 additions & 1 deletion src/ontology/go-edit.obo
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Expand Up @@ -210262,11 +210262,13 @@ relationship: part_of GO:0005654 ! nucleoplasm
id: GO:0035098
name: ESC/E(Z) complex
namespace: cellular_component
def: "A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4." [GOC:bf, GOC:sp, PMID:12408863, PMID:12408864, PMID:20064375]
def: "A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4." [GOC:bf, GOC:krc, GOC:sp, PMID:12408863, PMID:12408864, PMID:17107999, PMID:20064375, PMID:31123059, PMID:33232890]
synonym: "Extra Sex Combs/Enhancer of Zeste complex" EXACT []
synonym: "polycomb repressive complex 2" EXACT []
synonym: "PRC2 complex" EXACT [GOC:sp, PMID:20064375]
is_a: GO:0031519 ! PcG protein complex
is_a: GO:0035097 ! histone methyltransferase complex
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28327" xsd:anyURI

[Term]
id: GO:0035099
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Here's a diff of how these changes impact the classified ontology:

Ontology comparison

Left

  • Ontology IRI: http://purl.obolibrary.org/obo/go.owl
  • Version IRI: http://purl.obolibrary.org/obo/go/releases/2024-07-01/go.owl
  • Loaded from: file:/__w/go-ontology/go-ontology/src/ontology/../../reasoned-master.owl/reasoned.owl

Right

  • Ontology IRI: http://purl.obolibrary.org/obo/go.owl
  • Version IRI: http://purl.obolibrary.org/obo/go/releases/2024-07-01/go.owl
  • Loaded from: file:/__w/go-ontology/go-ontology/src/ontology/../../reasoned-pr.owl/reasoned.owl

Ontology imports

Ontology annotations

ESC/E(Z) complex http://purl.obolibrary.org/obo/GO_0035098

Removed

Added

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