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Updated all the broken links and confirmed they work -AO
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aolveraNIH committed Oct 4, 2024
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2 changes: 1 addition & 1 deletion tutorial_1-bismark.ipynb
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"\n",
"All four DNA strands that arise through bisulfite treatment and subsequent PCR amplification can be sequenced with the same frequency in non-directional libraries, while for directional libraries, adapters are attached to the DNA fragments such that only the original top or bottom strands will be sequenced. In the Bismark alignment step, `--directional` is set to default, so only report OT and OB strands.\n",
"\n",
"**Output alignment**. The output .bam files are the binary version of the SAM (Sequence Alignment/Map) format. Please see [here](https://github.com/FelixKrueger/Bismark/tree/master/Docs#bismark-bamsam-output-default) for more detailed explanation of the output .bam/.sam format, where the `XM-tag` is the methylation call string to indicate the methylated status of each C(tyosine) in different contexts: CG (or CpG), CHG or CHH (where H correspond to A, T or C). The methylation call string contains a dot ‘.’ for every position in the BS-read not involving a cytosine,\n",
"**Output alignment**. The output .bam files are the binary version of the SAM (Sequence Alignment/Map) format. Please see [here](https://github.com/FelixKrueger/Bismark/blob/master/docs/bismark/alignment.md#bismark-bamsam-output-default) for more detailed explanation of the output .bam/.sam format, where the `XM-tag` is the methylation call string to indicate the methylated status of each C(tyosine) in different contexts: CG (or CpG), CHG or CHH (where H correspond to A, T or C). The methylation call string contains a dot ‘.’ for every position in the BS-read not involving a cytosine,\n",
"or contains one of the following letters (z,Z,x,X,h,H) for the three different cytosine methylation contexts (UPPER CASE = METHYLATED, lower case = unmethylated).\n",
"> <img src=\"images/1_bismark_bam.png\" width=\"600\" />\n",
"\n",
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