Merge pull request #26 from wikipathways/add-figure-PMC4631354-3

Add figure PMC4631354_3

figure_fetch.log

@@ -410,3 +410,15 @@
 
 2024-09-09 22:27:05 - ==========================================================
 
+2024-09-10 00:09:30 - Starting NCBI PMC Single Figure Fetcher for PMC4631354 Figure 3
+
+2024-09-10 00:09:31 - Successfully downloaded image to figures/PMC4631354__pone.0141850.g003.jpg
+
+2024-09-10 00:09:31 - Successfully wrote YAML file to figures/PMC4631354__pone.0141850.g003.yml
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+2024-09-10 00:09:31 - Added PMC4631354__pone.0141850.g003 to keep_figids_for_ocr.txt
+
+2024-09-10 00:09:31 - NCBI PMC Single Figure Fetcher completed
+
+2024-09-10 00:09:31 - ==========================================================
+

figures/PMC4631354__pone.0141850.g003.yml

@@ -0,0 +1,34 @@
+---
+figid: PMC4631354__pone.0141850.g003
+pmcid: PMC4631354
+image_filename: PMC4631354__pone.0141850.g003.jpg
+figure_link: /pmc/articles/PMC4631354/figure/pone.0141850.g003/
+number: Fig 3
+figure_title: Characterization of SCDs as Membrane Maintenance Regulators
+caption: (A) The major FAs in C. elegans are produced by the elongation and desaturation
+  pathway shown here. An alternate pathway downstream of FA synthase (fasn-1) is used
+  for the production of monomethyl-branched chain FAs, C15iso and C17iso. (B) The
+  amount of new FA incorporated each hour was quantified in animals treated with adult-only
+  RNAi against the FA synthesis, elongation and desaturation genes for 48 hours. The
+  resulting data are summarized here with species with less replenishment than control
+  RNAi colored light blue (>25% decrease) and dark blue (>50% decrease). See S1 Dataset
+  for complete source data. (C) To determine the overall impact on membrane replenishment,
+  we averaged the replacement rates for each FA species and normalized by the abundance
+  of each species in the PL population. RNAi of pod-2, fat-5, fat-6 and fat-7 resulted
+  in significant reduction in overall membrane maintenance. (D) The relative amount
+  of synthesized FA is reduced with fat-7 RNAi treatment (blue) compared to control
+  RNAi (black). Numbers shown represent the mean of at least three experiments ± SEM.
+  Statistical significance was determined by two-tailed unpaired t-tests (*p<0.05,
+  **p<0.01, ***p<0.001)
+article_title: 13C- and 15N-Labeling Strategies Combined with Mass Spectrometry Comprehensively
+  Quantify Phospholipid Dynamics in C. elegans
+citation: Blair C. R. Dancy, et al. PLoS One. 2015;10(11).
+year: '2015'
+pub_date: 2015--
+epub_date: 2015-11-3
+doi: 10.1371/journal.pone.0141850
+journal_title: PLoS ONE
+journal_nlm_ta: PLoS One
+publisher_name: Public Library of Science
+keywords: []
+---

keep_figids_for_ocr.txt

@@ -1 +1,2 @@
 PMC9949038_3
+PMC4631354__pone.0141850.g003