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MAKE = make | ||
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CONTRIB = contrib | ||
PYDIR = idepi | ||
SUBDIRS = $(wildcard $(CONTRIB)/hmmer*) | ||
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all: | ||
@$(foreach var, $(SUBDIRS), make -C $(var) all;) | ||
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clean: | ||
@-$(foreach var, $(SUBDIRS), make -C $(var) clean;) | ||
@-rm $(PYDIR)/*.pyc | ||
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distclean: clean | ||
@-$(foreach var, $(SUBDIRS), make -C $(var) distclean;) | ||
@-rm $(PYDIR)/*.pyc |
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idepi :: (IDentify EPItope) python libraries containing some useful machine | ||
learning interfaces for regression and discrete analysis (including | ||
cross-validation, grid-search, and maximum-relevance/mRMR feature selection) | ||
and utilities to help identify neutralizing antibody epitopes via machine | ||
learning. | ||
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Copyright (C) 2011 N Lance Hepler <[email protected]> | ||
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This program is free software; you can redistribute it and/or modify | ||
it under the terms of the GNU General Public License as published by | ||
the Free Software Foundation; either version 2 of the License, or | ||
(at your option) any later version. | ||
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This program is distributed in the hope that it will be useful, | ||
but WITHOUT ANY WARRANTY; without even the implied warranty of | ||
MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the | ||
GNU General Public License for more details. | ||
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You should have received a copy of the GNU General Public License along | ||
with this program; if not, write to the Free Software Foundation, Inc., | ||
51 Franklin Street, Fifth Floor, Boston, MA 02110-1301 USA. |
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HMMER - Biological sequence analysis with profile hidden Markov models | ||
Copyright (C) 2010 Howard Hughes Medical Institute. | ||
------------------------------------------------------------------ | ||
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Additional copyrights apply to the entirety of the package: | ||
Copyright (C) 1992-2009 Sean R. Eddy | ||
Copyright (C) 2000-2009 Howard Hughes Medical Institute | ||
Copyright (C) 1992-2004 Washington University School of Medicine | ||
Copyright (C) 1992-1994 MRC Laboratory of Molecular Biology | ||
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The code includes contributions and input from the members of the | ||
HMMER development team and the Eddy/Rivas laboratories at HHMI Janelia | ||
Farm, whose current members include: | ||
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Sean Eddy Janelia Farm | ||
Sergi Castellano Janelia Farm | ||
Goran Ceric Janelia Farm | ||
Michael Farrar Janelia Farm | ||
Rob Finn Wellcome Trust Sanger Institute | ||
Bjarne Knudsen CLC bio | ||
Diana Kolbe Washington University/Janelia Farm | ||
Eric Nawrocki Janelia Farm | ||
Elena Rivas Janelia Farm | ||
Travis Wheeler Janelia Farm | ||
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HMMER also includes contributions from others, including copyrighted | ||
and licensed code and technology. These are noted in the appropriate | ||
places in source files. Contributors include: | ||
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Jeremy Buhler Washington University | ||
Ian Holmes UC Berkeley | ||
Erik Lindahl Stanford University | ||
Graeme Mitchison Cambridge University | ||
Lee Newberg Rensselaer Polytechnic Institute | ||
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Apple Computer Cupertino, CA | ||
Free Software Foundation, Inc. Cambridge, MA | ||
IBM TJ Watson Research Center Yorktown Heights, NY | ||
X Consortium Cambridge, MA | ||
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HMMER uses the Easel software library, which has its own license and | ||
copyright information. See easel/COPYRIGHT and easel/LICENSE. | ||
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HMMER includes patent-pending SIMD technology under nonexclusive | ||
license from Michael Farrar. You are sublicensed to use this | ||
technology specifically for the use, modification, and redistribution | ||
of HMMER3, under the terms of the GPLv3 patent clause. | ||
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This source code is distributed under the terms of the GNU General | ||
Public License. See the file LICENSE for details. | ||
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This program is free software: you can redistribute it and/or modify | ||
it under the terms of the GNU General Public License as published by | ||
the Free Software Foundation, either version 3 of the License, or (at | ||
your option) any later version. | ||
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This program is distributed in the hope that it will be useful, | ||
but WITHOUT ANY WARRANTY; without even the implied warranty of | ||
MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the | ||
GNU General Public License for more details. | ||
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A copy of the GNU General Public License is in the file LICENSE. You | ||
may also obtain a copy from <http://www.gnu.org/licenses/>. | ||
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"HMMER" is a trademark of the Howard Hughes Medical Institute. | ||
Although the code is freely available as open source, we intend that | ||
only the version at http://hmmer.org/ is known as HMMER. You are free | ||
to create a modified version and distribute it (subject to the terms | ||
of the GPL), but we ask that you name it something that would not be | ||
confused with HMMER itself. | ||
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------------------------------------------------------------------ | ||
The HMMER development team | ||
HHMI Janelia Farm Research Campus | ||
http://hmmer.org/ | ||
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Brief installation instructions | ||
HMMER 3.0; March 2010 | ||
SRE, Mon Mar 24 09:29:34 2008 | ||
------------------------------------------------------------- | ||
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These are quick installation instructions. For complete documentation, | ||
including customization and troubleshooting, see the Installation | ||
chapter in the HMMER User's Guide (Userguide.pdf). | ||
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Starting from a source distribution, hmmer-3.0.tar.gz: | ||
uncompress: uncompress hmmer-3.0.tar.gz | ||
unpack: tar xf hmmer-3.0.tar | ||
move into new directory: cd hmmer-3.0 | ||
configure: ./configure | ||
build: make | ||
automated tests: make check | ||
automated install: make install | ||
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HMMER is developed primarily on Linux and Mac OS/X systems. It is | ||
tested on a variety of UNIX and UNIX-like operating systems. It is | ||
written in ANSI C99 conforming to POSIX standards. It is meant to be | ||
portable to any POSIX-compliant system with an ANSI C99 compiler, | ||
including all UNIX and Macintosh systems. It should also build on | ||
Windows systems with optional POSIX compatibility software installed, | ||
such as Cygwin. | ||
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------------------------------------------------------------- | ||
Starting from a Subversion (SVN) working copy: | ||
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If you have checked HMMER out from its Subversion repository, there's | ||
some additional stuff you need to do one-time-only in your new working | ||
directory: | ||
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ln -s easel/aclocal.m4 aclocal.m4 | ||
autoconf | ||
(cd easel; autoconf) | ||
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------------------------------------------------------------- | ||
Brief notes on different ways we configure HMMER during development: | ||
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for production: ./configure CC=icc LDFLAGS="-static" | ||
icc (Intel C compiler) is best, for optimal performance | ||
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for debugging: ./configure --enable-debugging | ||
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for profiling: ./configure CFLAGS="-g -pg -O" | ||
make | ||
(run benchmark program; then gprof the program) | ||
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------------------------------------------------------------- | ||
The HMMER development team | ||
HHMI Janelia Farm Research Campus | ||
http://hmmer.org/ | ||
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