Skip to content

Commit

Permalink
added comparisons and robustness
Browse files Browse the repository at this point in the history
  • Loading branch information
falexwolf committed Jun 27, 2018
1 parent 61dbf3a commit 34d26cf
Show file tree
Hide file tree
Showing 12 changed files with 6,031 additions and 0 deletions.
348 changes: 348 additions & 0 deletions comparisons/nestorowa16_monocle2/nestorowa16_monocle2.ipynb

Large diffs are not rendered by default.

454 changes: 454 additions & 0 deletions comparisons/paul15_monocle2/monocle2_alternative.ipynb

Large diffs are not rendered by default.

516 changes: 516 additions & 0 deletions comparisons/paul15_monocle2/monocle2_original.ipynb

Large diffs are not rendered by default.

328 changes: 328 additions & 0 deletions comparisons/simulated_data/_exports.ipynb

Large diffs are not rendered by default.

237 changes: 237 additions & 0 deletions comparisons/simulated_data/dpt.ipynb

Large diffs are not rendered by default.

15 changes: 15 additions & 0 deletions comparisons/simulated_data/eclair/README.md
Original file line number Diff line number Diff line change
@@ -0,0 +1,15 @@
# Comparison with ECLAIR [(Giecold *et al.*, Nucl. Acids Research, 2016)](https://doi.org/10.1093/nar/gkw452)

## Contents

* [*eclair_plots*](eclair_plots.ipynb) visualizes the results of running eclair
* [*logfile_run_X_krumsiek11_scaled.txt*](logfile_run_X_krumsiek11_scaled.txt) shows the logging output and the parameters that allow to reproduce the results discussed [here](../)
* [*X_krumsiek11_scaled.txt*](X_krumsiek11_scaled.txt) contains the scaled data matrix for the simple tree, [*X_krumsiek11.txt*](X_krumsiek11.txt) contains the equivalent unscaled matrix and [*X_krumsiek11_blobs.txt*](X_krumsiek11_blobs.txt) contains the data describing tree and clusters; all in tab-separated format as required by ECLAIR. These files have been generated in [*../../comparisons_exports*](../../comparisons_exports.ipynb), which also provides visualizations of the data.

## Notes

* See the discussion of the results [here](../).

* We acknowledge help by G. Giecold and S. P. Garcia, who adviced to scale the data matrix and provided default parameters. Parst of the correspondence are archived here: https://github.com/GGiecold/ECLAIR/issues/3

* The algorithm could not handle the unnormalized data matrices [*X_krumsiek11.txt*](X_krumsiek11.txt) and [*X_krumsiek11_blobs.txt*](X_krumsiek11_blobs.txt).
312 changes: 312 additions & 0 deletions comparisons/simulated_data/eclair/logfile_run_X_krumsiek11_scaled.txt

Large diffs are not rendered by default.

509 changes: 509 additions & 0 deletions comparisons/simulated_data/monocle2.ipynb

Large diffs are not rendered by default.

15 changes: 15 additions & 0 deletions comparisons/simulated_data/stemID/README.md
Original file line number Diff line number Diff line change
@@ -0,0 +1,15 @@
# Comparison with stemID 2

Reproduce the comparison with stemID 2, the successor of stemID [(Grün *et al.*, Cell. Stem Cell,
2016)](https://doi.org/10.1016/j.stem.2016.05.010),
by running [*RaceID3_StemID2_sample.R*](RaceID3_StemID2_sample.R).
```
time Rscript RaceID3_StemID2_sample.R
```
See [*logfile_X_krumsiek11_blobs_shifted.txt*](*logfile_X_krumsiek11_blobs_shifted.txt*) for the logging output that we produced.

We acknowledge D. Grün for providing the code via Email; parameters were chosen
by D. Grün so that stemID would produce sensible results. The code is an
improved version of the original stemID, which is available from https://github.com/dgrun/StemID/.

We note that we also tried running the code on the simpler data file *X_krumsiek11_shifted.csv* with the same parameters, but were not able to do so as this resulted in errors.
Loading

0 comments on commit 34d26cf

Please sign in to comment.