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Arina Danilina committed May 13, 2024
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Expand Up @@ -12,32 +12,77 @@ moscot builds upon three principles:

### Biological problems

#### Temporal data

```{eval-rst}
.. list-table::
:widths: 15 100 25
:widths: 15 100
:header-rows: 1
* - Problem
- Description
- Module
* - :mod:`moscot.problems.time.TemporalProblem`
- Class for analyzing time-series single cell data based on :cite:p:`schiebinger:19`
- module:: moscot.problems.time
- Class for analyzing time-series single cell data based on :cite:`schiebinger:19`.
* - :mod:`moscot.problems.time.LineageProblem`
- Estimator for modelling time series single cell data based on :cite:`lange-moslin:23`.
```

#### Spatial data

```{eval-rst}
.. list-table::
:widths: 15 100
:header-rows: 1
* - Problem
- Description
* - :mod:`moscot.problems.space.AlignmentProblem`
- Class for aligning spatial omics data, based on :cite:`zeira:22`.
* - :mod:`moscot.problems.space.MappingProblem`
- Class for mapping single cell omics data onto spatial data, based on :cite:`nitzan:19`.
```

#### Spatiotemporal data

```{eval-rst}
.. list-table::
:widths: 15 100
:header-rows: 1
* - Problem
- Description
* - :mod:`moscot.problems.cross_modality.TranslationProblem`
- Class for analyzing time series spatial single-cell data.
```

#### Multimodal data

```{eval-rst}
.. list-table::
:widths: 15 100
:header-rows: 1
* - Problem
- Description
* - :mod:`moscot.problems.spatiotemporal.SpatioTemporalProblem`
- Class for integrating single-cell multi-omics data, based on :cite:`demetci-scot:22`.
```

### Generic problems

```{eval-rst}
.. list-table::
:widths: 15 100 25
:widths: 15 100
:header-rows: 1
* - Problem
- Description
- Module
* - :mod:`moscot.problems.generic.SinkhornProblem`
- Class for solving a :term:`linear problem`.
- module:: moscot.problems.generic
* - :mod:`moscot.problems.generic.GWProblem`
- Class for solving a :term:`Gromov-Wasserstein` problem.
* - :mod:`moscot.problems.generic.FGWProblem`
- Class for solving a :term:`fused Gromov-Wasserstein` problem.
```

## Scalability
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