oncoEnrichR is an R package for functional interrogation of human gene lists in the context of cancer. The package leverages an extensive amount of prior molecular knowledge that allows for biological interpretation along multiple dimensions, both at the systems level and at the level of individual genes.
Web-based access to oncoEnrichR is available at https://oncotools.elixir.no
oncoEnrichR is primarily intended for exploratory analysis and prioritization of a gene list (referred to here as query set) from high-throughput cancer biology experiments, e.g. CRISPR screens, protein proximity labeling, or gene expression profiling. The tool queries a number of high-quality data resources in order to assemble cancer-relevant annotations and analyses in an interactive report.
- What types of questions can be answered by oncoEnrichR?
- Output views from oncoEnrichR
- Installation instructions
- Running instructions
- Annotation resources available in oncoEnrichR
- September 9th 2024 1.5.2 release
- August 3rd 2024 1.5.1 release
- August 16th 2023: 1.4.2 release
- June 18th 2023: 1.4.1 release
If you use oncoEnrichR, please cite the following publication:
Sigve Nakken, Sveinung Gundersen, Fabian L. M. Bernal, Dimitris Polychronopoulos, Eivind Hovig, and Jørgen Wesche. Comprehensive interrogation of gene lists from genome-scale cancer screens with oncoEnrichR (2023). Int J Cancer. doi:10.1002/ijc.34666
sigven AT ifi.uio.no
oncoEnrichR is supported by the Centre for Cancer Cell Reprogramming at the University of Oslo/Oslo University Hospital, and Elixir Norway (Oslo node).
