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pgxo.owl
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pgxo.owl
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<?xml version="1.0"?>
<rdf:RDF xmlns="http://pgxo.loria.fr/"
xml:base="http://pgxo.loria.fr/"
xmlns:dc="http://purl.org/dc/elements/1.1/"
xmlns:ro="http://purl.obolibrary.org/obo/"
xmlns:dul="http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#"
xmlns:owl="http://www.w3.org/2002/07/owl#"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:xml="http://www.w3.org/XML/1998/namespace"
xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
xmlns:pgxo="http://pgxo.loria.fr/"
xmlns:prov="http://www.w3.org/ns/prov#"
xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#">
<owl:Ontology rdf:about="http://pgxo.loria.fr/">
<dc:creator>Adrien Coulet, Loria - Inria, Université de Lorraine</dc:creator>
<dc:creator>Clément Jonquet, LIRMM, Université de Montpellier</dc:creator>
<dc:creator>Pierre Monnin, Loria (CNRS, Inria Nancy-Grand Est, Université de Lorraine)</dc:creator>
<dc:license>https://creativecommons.org/licenses/by-nc/4.0/</dc:license>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Change pgxo:causes to a set of potential relationships
- more granularity added
- add negative relationships (not semantically defined) e.g. isNotAssociatedWith (note that isAssociatedWith is not defined as disjoint with isNotAssociatedWith whereas it could be)</rdfs:comment>
<rdfs:comment>PGxO aims at providing a small set of concepts and roles that may type elements of pharmacogenomic relationships.</rdfs:comment>
<rdfs:label>PGxO: a lite Pharmacogenomic Ontology</rdfs:label>
<owl:versionInfo rdf:datatype="http://www.w3.org/2001/XMLSchema#string">0.5</owl:versionInfo>
</owl:Ontology>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Annotation properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.org/dc/elements/1.1/creator -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/creator"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Object Properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://pgxo.loria.fr/causes -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/causes">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/influences"/>
<owl:inverseOf rdf:resource="http://pgxo.loria.fr/isCausedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/decreases -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/decreases">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/influences"/>
<owl:inverseOf rdf:resource="http://pgxo.loria.fr/isDecreasedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/decreasesChanceOf -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/decreasesChanceOf">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/influences"/>
<owl:inverseOf rdf:resource="http://pgxo.loria.fr/hasChanceDecreasedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/doesNotCause -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/doesNotCause">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/doesNotInfluence"/>
<owl:inverseOf rdf:resource="http://pgxo.loria.fr/isNotCausedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/doesNotDecrease -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/doesNotDecrease">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/doesNotInfluence"/>
<owl:inverseOf rdf:resource="http://pgxo.loria.fr/isNotDecreasedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/doesNotDecreaseChanceOf -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/doesNotDecreaseChanceOf">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/doesNotInfluence"/>
<owl:inverseOf rdf:resource="http://pgxo.loria.fr/hasNotChanceDecreasedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/doesNotIncrease -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/doesNotIncrease">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/doesNotInfluence"/>
<owl:inverseOf rdf:resource="http://pgxo.loria.fr/isNotIncreasedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/doesNotIncreaseChanceOf -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/doesNotIncreaseChanceOf">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/doesNotInfluence"/>
<owl:inverseOf rdf:resource="http://pgxo.loria.fr/hasNotChanceIncreasedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/doesNotInfluence -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/doesNotInfluence">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isNotAssociatedWith"/>
<owl:inverseOf rdf:resource="http://pgxo.loria.fr/isNotInfluencedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/doesNotMetabolize -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/doesNotMetabolize">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/doesNotInfluence"/>
<owl:inverseOf rdf:resource="http://pgxo.loria.fr/isNotMetabolizedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/doesNotTransport -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/doesNotTransport">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/doesNotInfluence"/>
<owl:inverseOf rdf:resource="http://pgxo.loria.fr/isNotTransportedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/doesNotTreat -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/doesNotTreat">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isNotAssociatedWith"/>
<owl:inverseOf rdf:resource="http://pgxo.loria.fr/isNotTreatedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/hasChanceDecreasedBy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/hasChanceDecreasedBy">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isInfluencedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/hasChanceIncreasedBy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/hasChanceIncreasedBy">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isInfluencedBy"/>
<owl:inverseOf rdf:resource="http://pgxo.loria.fr/increasesChanceOf"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/hasNotChanceDecreasedBy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/hasNotChanceDecreasedBy">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isNotInfluencedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/hasNotChanceIncreasedBy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/hasNotChanceIncreasedBy">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isNotInfluencedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/increases -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/increases">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/influences"/>
<owl:inverseOf rdf:resource="http://pgxo.loria.fr/isIncreasedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/increasesChanceOf -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/increasesChanceOf">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/influences"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/influences -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/influences">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isAssociatedWith"/>
<owl:inverseOf rdf:resource="http://pgxo.loria.fr/isInfluencedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/isAssociatedWith -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/isAssociatedWith">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#SymmetricProperty"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/isCausedBy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/isCausedBy">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isInfluencedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/isDecreasedBy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/isDecreasedBy">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isInfluencedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/isIncreasedBy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/isIncreasedBy">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isInfluencedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/isInfluencedBy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/isInfluencedBy">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isAssociatedWith"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/isMetabolizedBy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/isMetabolizedBy">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isInfluencedBy"/>
<owl:inverseOf rdf:resource="http://pgxo.loria.fr/metabolizes"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/isNotAssociatedWith -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/isNotAssociatedWith">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#SymmetricProperty"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/isNotCausedBy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/isNotCausedBy">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isNotInfluencedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/isNotDecreasedBy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/isNotDecreasedBy">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isNotInfluencedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/isNotIncreasedBy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/isNotIncreasedBy">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isNotInfluencedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/isNotInfluencedBy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/isNotInfluencedBy">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isNotAssociatedWith"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/isNotMetabolizedBy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/isNotMetabolizedBy">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isNotInfluencedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/isNotTransportedBy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/isNotTransportedBy">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isNotInfluencedBy"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/isNotTreatedBy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/isNotTreatedBy">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isNotAssociatedWith"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/isTransportedBy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/isTransportedBy">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isInfluencedBy"/>
<owl:inverseOf rdf:resource="http://pgxo.loria.fr/transports"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/isTreatedBy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/isTreatedBy">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isAssociatedWith"/>
<owl:inverseOf rdf:resource="http://pgxo.loria.fr/treats"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/metabolizes -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/metabolizes">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/influences"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/qualifiedProxy -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/qualifiedProxy"/>
<!-- http://pgxo.loria.fr/qualifiedVariation -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/qualifiedVariation"/>
<!-- http://pgxo.loria.fr/transports -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/transports">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/influences"/>
</owl:ObjectProperty>
<!-- http://pgxo.loria.fr/treats -->
<owl:ObjectProperty rdf:about="http://pgxo.loria.fr/treats">
<rdfs:subPropertyOf rdf:resource="http://pgxo.loria.fr/isAssociatedWith"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/BFO_0000050 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000050">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdfs:label xml:lang="en">part of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/BFO_0000051 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
<rdfs:label xml:lang="en">has part</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002502 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002502">
<rdfs:label xml:lang="en">depends on</rdfs:label>
</owl:ObjectProperty>
<!-- http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#hasQuality -->
<owl:ObjectProperty rdf:about="http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#hasQuality">
<rdfs:domain rdf:resource="http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#Entity"/>
<rdfs:range rdf:resource="http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#Quality"/>
<rdfs:label xml:lang="en">has quality</rdfs:label>
</owl:ObjectProperty>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Data properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#hasDataValue -->
<owl:DatatypeProperty rdf:about="http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#hasDataValue">
<rdfs:domain rdf:resource="http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#Entity"/>
<rdfs:label xml:lang="en">has data value</rdfs:label>
</owl:DatatypeProperty>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Classes
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://pgxo.loria.fr/Disease -->
<owl:Class rdf:about="http://pgxo.loria.fr/Disease">
<rdfs:subClassOf rdf:resource="http://pgxo.loria.fr/Phenotype"/>
<rdfs:label>Disease</rdfs:label>
</owl:Class>
<!-- http://pgxo.loria.fr/Drug -->
<owl:Class rdf:about="http://pgxo.loria.fr/Drug">
<rdfs:label>Drug</rdfs:label>
</owl:Class>
<!-- http://pgxo.loria.fr/Gene -->
<owl:Class rdf:about="http://pgxo.loria.fr/Gene">
<rdfs:subClassOf rdf:resource="http://pgxo.loria.fr/GeneticFactor"/>
<rdfs:label>Gene</rdfs:label>
</owl:Class>
<!-- http://pgxo.loria.fr/GeneticFactor -->
<owl:Class rdf:about="http://pgxo.loria.fr/GeneticFactor">
<rdfs:label>Genetic factor</rdfs:label>
</owl:Class>
<!-- http://pgxo.loria.fr/GenomicVariation -->
<owl:Class rdf:about="http://pgxo.loria.fr/GenomicVariation">
<rdfs:subClassOf rdf:resource="http://pgxo.loria.fr/GeneticFactor"/>
<rdfs:label>Genomic variation</rdfs:label>
</owl:Class>
<!-- http://pgxo.loria.fr/Haplotype -->
<owl:Class rdf:about="http://pgxo.loria.fr/Haplotype">
<rdfs:subClassOf rdf:resource="http://pgxo.loria.fr/GenomicVariation"/>
<rdfs:label>Haplotype</rdfs:label>
</owl:Class>
<!-- http://pgxo.loria.fr/PharmacodynamicPhenotype -->
<owl:Class rdf:about="http://pgxo.loria.fr/PharmacodynamicPhenotype">
<rdfs:subClassOf rdf:resource="http://pgxo.loria.fr/Phenotype"/>
<rdfs:label>Pharmacodynamic phenotype</rdfs:label>
</owl:Class>
<!-- http://pgxo.loria.fr/PharmacogenomicRelationship -->
<owl:Class rdf:about="http://pgxo.loria.fr/PharmacogenomicRelationship">
<rdfs:subClassOf rdf:resource="http://www.w3.org/ns/prov#Entity"/>
<rdfs:label>Pharmacogenomic relationship</rdfs:label>
</owl:Class>
<!-- http://pgxo.loria.fr/PharmacokineticPhenotype -->
<owl:Class rdf:about="http://pgxo.loria.fr/PharmacokineticPhenotype">
<rdfs:subClassOf rdf:resource="http://pgxo.loria.fr/Phenotype"/>
<rdfs:label>Pharmacokinetic phenotype</rdfs:label>
</owl:Class>
<!-- http://pgxo.loria.fr/Phenotype -->
<owl:Class rdf:about="http://pgxo.loria.fr/Phenotype">
<rdfs:label>Phenotype</rdfs:label>
</owl:Class>
<!-- http://pgxo.loria.fr/Variant -->
<owl:Class rdf:about="http://pgxo.loria.fr/Variant">
<rdfs:subClassOf rdf:resource="http://pgxo.loria.fr/GenomicVariation"/>
<rdfs:label>Variant</rdfs:label>
</owl:Class>
<!-- http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#Entity -->
<owl:Class rdf:about="http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#Entity">
<rdfs:label xml:lang="en">Entity</rdfs:label>
</owl:Class>
<!-- http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#Quality -->
<owl:Class rdf:about="http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#Quality">
<rdfs:subClassOf rdf:resource="http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#Entity"/>
<rdfs:label xml:lang="en">Quality</rdfs:label>
</owl:Class>
<!-- http://www.w3.org/ns/prov#Entity -->
<owl:Class rdf:about="http://www.w3.org/ns/prov#Entity"/>
<!-- http://www.w3.org/ns/prov#Generation -->
<owl:Class rdf:about="http://www.w3.org/ns/prov#Generation">
<rdfs:subClassOf rdf:resource="http://www.ontologydesignpatterns.org/ont/dul/DUL.owl#Entity"/>
</owl:Class>
</rdf:RDF>
<!-- Generated by the OWL API (version 4.5.6.2018-09-06T00:27:41Z) https://github.com/owlcs/owlapi -->