Releases: oncokb/oncokb-public
Releases · oncokb/oncokb-public
Change to HTML5Mode
update link Signed-off-by: Hongxin Zhang <[email protected]>
January 24, 2019 Updates
- Lorlatinib FDA-approval in ALK-positive metastatic NSCLC added as a new Level 1 association.
- Addition of 16 new heme-associated genes
December 14, 2018 Updates
- Inclusion of NTRK1 and NTRK3 Level R2 alterations to the Actionable Genes page
- Updated actionable genes table.
- Addition of 25 new heme-associated genes
November 2, 2018 Updates
LOXO-292 for RET fusion–positive non–small cell lung cancer (NSCLC) added.
October 26, 2018 Updates
- Level R2 alterations in ALK, EGFR, and MET are now included in the Actionable Genes page
- Updated actionable genes table.
- Addition of 9 new heme-associated genes
- OncoTree updated from version 2017_06_21 to version 2018_06_15
October 1, 2018 Updates
- Added 27 heme genes
- Updated actionable genes table.
August 20, 2018 Updates
- One level 1 association
- Added 42 heme genes
- Positioned Variants are included. Example:
http://oncokb.org/#/gene/BRAF/alteration/V600E - Updated actionable genes table. Now the treatments are grouped together based on gene+alteration+tumor type
July 12, 2018 Updates
- Updated Actionable Genes
- New Level 4 associations have been added
- Inclusion of Level R1 actionable variants in Actionable Genes
February 2, 2018 Updates
- Updated Actionable Genes
- Addition of a new gene: KLF5 (Zhang et al., Cancer Discovery, 2017)
- Addition of new variants and updates to existing variants
August 17, 2017 Updates
- Several FDA-approvals have been incorporated into the Actionable Genes table, see News for more details.
- Introduced a curated list of cancer genes.
- Addition of gene-variants pages with variant level annotation. e.g. BRAF V600E.
- Improved search box that queries genes and variants.
