##bcall Call variants using a site-specific binomial model. bcall uses the Rmath libraries for the pbinom function and uses cereal for serializing C++ objects and storing them to disk.

Install

git clone --recursive https://github.com/gatoravi/bcall
mkdir build && cd build && cmake .. && make

Usage

Get all options

./bcall

Estimate priors on fixed sites

./bcall prior-dump-fixed samples_rclist.tsv dump_output SeqCap_EZ_Exome_v3_primary.bed.gz

To call mutations using the merged priors

./bcall call-using-merged sample_readcountfile_list.tsv merged_priors.dump