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Update dIF definition
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jesseangelis committed Jun 6, 2024
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Expand Up @@ -191,7 +191,7 @@ Prior to DEXSeq DTU analysis, filtering of genes and features with low expressio
### IsoformSwitchAnalyzeR

IsoformSwitchAnalyzeR as described by [Vitting-Seerup et al., 2019](https://doi.org/10.1093/bioinformatics/btz247) performs a genome-wide analysis of splicing patterns and identifies isoform switches. It takes a salmon results directory as input so either `--source fastq` or `--source salmon_results` must be given. Two parameters can be set:
`--isoformswitchanalyzer_alpha` sets the significance threshold and `--isoformswitchanalyzer_dIF` sets the minimum absolute difference in isoform expression.
`--isoformswitchanalyzer_alpha` sets the significance threshold and `--isoformswitchanalyzer_dIF` sets the minimum absolute difference in isoform usage.

## Event based approaches

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