MetaCache v0.8.0
New feature "Coverage Filter"
Option -cov-percentile <p>
removes the p-th percentile of hit targets (reference genomes) with the lowest coverage. A first pass does the normal mapping of queries (reads) to targets (reference genomes). The actual classification is then done in a second pass using only the remaining hit targets.
This will lead to a very small increase in runtime and memory consumption but can improve accuracy by detecting and removing stray false positive hits.
The coverage filter is deactivated by default.
Other Changes
- improved multi-threading in query mode
- improved database format (layout better suited for future loading on GPUs)
- code cleanup