Skip to content

Based on a range of model parameters covering both intravenous and oral administration, simulate a multiple dose pharmacokinetic profile and calculate the time within the pre-specified therapeutic window at steady state.

License

Notifications You must be signed in to change notification settings

michielve/PK_therapeutic_window

Folders and files

NameName
Last commit message
Last commit date

Latest commit

 

History

7 Commits
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Repository files navigation

PK_therapeutic_window repository by PMXSolutions.com

This Shiny application was created to assist in the simulation of pharmacokinetic profiles and the exploration of different dosing regimens with different parameters.

The latest version of this repository is being hosted on pmxsolutions.com

Due to the great functionality and ease-of-use, all simulations were based on mrgsolve.

Run application

Download, clone, or fork this repository to use the R code within your local R installation.

Furthermore, the runGitHub command from the Shiny package can be used to immediately execute the latest version from within R:

library(shiny)

runGitHub("PK_therapeutic_window", "michielve")

Required software

Make sure mrgsolve is installed and working on your computer: https://github.com/metrumresearchgroup/mrgsolve/wiki/mrgsolve-Installation

Contribute

Feel free to use and improve this repository to include additional functionality. Report bugs in the issues section of this repository.

About

Based on a range of model parameters covering both intravenous and oral administration, simulate a multiple dose pharmacokinetic profile and calculate the time within the pre-specified therapeutic window at steady state.

Resources

License

Stars

Watchers

Forks

Releases

No releases published

Packages

No packages published