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Update to description file with ORCIDs, first kalis paper, and bug re…
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louisaslett committed Oct 2, 2024
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28 changes: 16 additions & 12 deletions DESCRIPTION
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Expand Up @@ -3,23 +3,27 @@ Type: Package
Title: High Performance Li & Stephens Local Ancestry Inference
Version: 2.0.0
Authors@R: c(person("Louis", "Aslett", role = c("aut", "cre"),
email = "[email protected]"),
email = "[email protected]",
comment = c(ORCID = "0000-0003-2211-233X")),
person("Ryan", "Christ", role = "aut",
email = "[email protected]"))
email = "[email protected]",
comment = c(ORCID = "0000-0002-2049-3389")))
Author: Louis Aslett [aut, cre],
Ryan Christ [aut]
Maintainer: Louis Aslett <[email protected]>
Description: kalis provides a high performance implementation of the Li &
Stephens model <https://www.ncbi.nlm.nih.gov/pubmed/14704198> for local
ancestry inference (local referring to a region of the genome). For a set of N
phased haplotypes, kalis computes the posterior marginal probability of each
haplotype copying every other haplotype by running N hidden Markov models in
parallel. This yields an N x N distance matrix that summarizes the recent
local ancestry at each variant of interest. The package provides functionality
for specifying a recombination map, site-specific mutation rates, and
differing prior copying probabilities for each recipient haplotype. Extensive
use is made of low level threading and CPU vector instructions.
Description: kalis <doi:10.1186/s12859-024-05688-8> provides a high performance
implementation of the Li & Stephens model <doi:10.1093/genetics/165.4.2213>
for local ancestry inference (local referring to a region of the genome). For
a set of N phased haplotypes, kalis computes the posterior marginal
probability of each haplotype copying every other haplotype by running N
hidden Markov models in parallel. This yields an N x N distance matrix that
summarizes the recent local ancestry at each variant of interest. The package
provides functionality for specifying a recombination map, site-specific
mutation rates, and differing prior copying probabilities for each recipient
haplotype. Extensive use is made of low level threading and CPU vector
instructions.
License: GPL (>= 3)
BugReports: https://github.com/louisaslett/kalis/issues
URL: https://kalis.louisaslett.com/, https://github.com/louisaslett/kalis
LazyData: TRUE
Depends: R (>= 3.5.0)
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