This workflow implements the METAGEM (META-analysis of GEM summary statistics) tool. METAGEM is a software program for meta-analysis of large-scale gene-environment interaction testing results, including multi-exposure interaction, joint, and marginal tests. It uses results directly from GEM output.

Authors: Duy Pham, Kenny Westerman

METAGEM tool information:

• Source code: https://github.com/large-scale-gxe-methods/METAGEM

Inputs:

See the "parameter_meta" section of the .wdl script.

Outputs:

• A summary statistics file containing the meta-analysis results.