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Merge pull request #683 from girder/lilian-fixes
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Apply paper draft fixes from Lilian
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waxlamp authored Oct 9, 2020
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24 changes: 11 additions & 13 deletions joss/paper.md
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## Data Imputation

Once errors are corrected, data imputation is automatically performed.
For metabolites with missing values, the type of missingness is classified as
Once errors are corrected, data imputation is automatically performed. For
metabolites with missing values, the type of missingness is classified as
missing completely at random (MCAR) or missing not at random (MNAR). For each
type, an imputation mode is automatically performed but the options may be
adjusted to apply different algorithms, including
random
forest, KNN, mean, or median imputation modes for completely at random
missingness (MCAR) and zero or half-minimum imputation for not-at-random
missingness (MNAR).
adjusted to apply different algorithms, including random forest, K neareset
neighbors, mean, or median imputation modes for completely at random missingness
(MCAR) and zero or half-minimum imputation for not-at-random missingness (MNAR).

![Dynamically updating customizable plots which animate to show
immediate feedback when adjusting pretreatment options.](figures/figure3.png)
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which include MS spectral processing and have statistical analyses and
visualization tools that are generally similar to Viime.

An exhaustive feature comparison of with these other platforms is beyond the
scope of this paper, but a major distinguishing feature of Viime is its emphasis
on ease of use and interactivity. Only XCMS and MetaboAnalyst are simple,
readily accessible web applications that require no existing package (e.g. R),
downloads or connection to the Galaxy platform. The unique user interactivity in
Viime starts with the ability to simply drag and drop CSV or Excel files and
An exhaustive feature comparison with these other platforms is beyond the scope
of this paper, but a major distinguishing feature of Viime is its emphasis on
ease of use and interactivity. Only XCMS and MetaboAnalyst are simple, readily
accessible web applications that require no existing package (e.g. R), downloads
or connection to the Galaxy platform. The unique user interactivity in Viime
starts with the ability to simply drag and drop CSV or Excel files and
interactively assign the sample identifiers, comparison groups, metadata, and
metabolites. Dynamic visualization of the PCA scores and loadings plots with
different types of data (e.g. NMR, LC-MS, and GC-MS) and data treatments (e.g.
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