Merge pull request #27820 from geneontology/issue-27819

removed brenda xrefs fixes #27819

src/ontology/go-edit.obo

@@ -45231,7 +45231,6 @@ def: "Catalysis of the reaction: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ = 5
 synonym: "6,7-dimethyl-8-(1-D-ribityl)lumazine:6,7-dimethyl-8-(1-D-ribityl)lumazine 2,3-butanediyltransferase activity" RELATED [EC:2.5.1.9]
 synonym: "heavy riboflavin synthase" NARROW [EC:2.5.1.9]
 synonym: "light riboflavin synthase" NARROW [EC:2.5.1.9]
-synonym: "lumazine synthase activity" BROAD [BRENDA:2.5.1.9]
 synonym: "riboflavin synthetase activity" RELATED [EC:2.5.1.9]
 synonym: "riboflavine synthase activity" RELATED [EC:2.5.1.9]
 synonym: "riboflavine synthetase activity" RELATED [EC:2.5.1.9]
@@ -53203,7 +53202,7 @@ relationship: part_of GO:0005886 ! plasma membrane
 id: GO:0005601
 name: classical-complement-pathway C3/C5 convertase complex
 namespace: cellular_component
-def: "A heterodimeric protein complex that catalyzes the cleavage of complement components C3 and C5, and acts in the classical pathway of complement activation; consists of one monomer of C2a and one monomer of C4b; C2a is the catalytic subunit, but cannot catalyze cleavage alone." [BRENDA:3.4.21.43, GOC:mah]
+def: "A heterodimeric protein complex that catalyzes the cleavage of complement components C3 and C5, and acts in the classical pathway of complement activation; consists of one monomer of C2a and one monomer of C4b; C2a is the catalytic subunit, but cannot catalyze cleavage alone." [GOC:mah]
 is_a: GO:1902494 ! catalytic complex
 relationship: part_of GO:0005576 ! extracellular region
 relationship: part_of GO:0005615 ! extracellular space
@@ -55595,7 +55594,7 @@ is_a: GO:1902494 ! catalytic complex
 id: GO:0005836
 name: fatty-acyl-CoA synthase complex
 namespace: cellular_component
-def: "A protein complex that possesses fatty-acyl-CoA synthase activity." [BRENDA:2.3.1.86, GOC:mah]
+def: "A protein complex that possesses fatty-acyl-CoA synthase activity." [GOC:mah]
 comment: Note that fatty acid synthetases of vertebrates and yeast are stable enzyme complexes of multifunctional polypeptide chains, whereas the fatty acid synthetases of plants and E. coli consist of non-associated individual enzymes.
 synonym: "fatty acyl CoA synthase complex" EXACT []
 intersection_of: GO:1902494 ! catalytic complex
@@ -56667,7 +56666,7 @@ replaced_by: GO:0045252
 id: GO:0005948
 name: acetolactate synthase complex
 namespace: cellular_component
-def: "A dimeric (a large and a small chain) or tetrameric (two large and two small chains) enzyme complex. Catalyzes the formation of acetolactate from pyruvate." [BRENDA:2.2.1.6, GOC:jl, PMID:16458324, PMID:8756689]
+def: "A dimeric (a large and a small chain) or tetrameric (two large and two small chains) enzyme complex. Catalyzes the formation of acetolactate from pyruvate." [GOC:jl, PMID:16458324, PMID:8756689]
 comment: See also the molecular function term 'acetolactate synthase activity ; GO:0003984'.
 synonym: "acetohydroxyacid synthase complex" EXACT []
 intersection_of: GO:0032991 ! protein-containing complex
@@ -56885,7 +56884,7 @@ relationship: part_of GO:0005737 ! cytoplasm
 id: GO:0005971
 name: ribonucleoside-diphosphate reductase complex
 namespace: cellular_component
-def: "An enzyme complex composed of 2-4 or more subunits, which usually contains nonheme iron and requires ATP for catalysis. Catalyzes the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor." [BRENDA:1.17.4.1]
+def: "An enzyme complex composed of 2-4 or more subunits, which usually contains nonheme iron and requires ATP for catalysis. Catalyzes the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor." [PMID:10716984, PMID:21336276]
 synonym: "ribonucleotide reductase complex" EXACT [GOC:mah]
 synonym: "RNR complex" EXACT [GOC:mah]
 intersection_of: GO:0032991 ! protein-containing complex
@@ -89495,7 +89494,7 @@ replaced_by: GO:0009410
 id: GO:0009316
 name: 3-isopropylmalate dehydratase complex
 namespace: cellular_component
-def: "A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate." [BRENDA:4.2.1.33, GOC:jl, MetaCyc:3-ISOPROPYLMALISOM-CPLX, PMID:7026530]
+def: "A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate." [GOC:jl, MetaCyc:3-ISOPROPYLMALISOM-CPLX, PMID:7026530]
 comment: See also the molecular function term '3-isopropylmalate dehydratase activity ; GO:0003861'.
 synonym: "isopropylmalate isomerase complex" EXACT []
 xref: MetaCyc:3-ISOPROPYLMALISOM-CPLX
@@ -89606,7 +89605,7 @@ property_value: term_tracker_item "https://github.com/geneontology/go-ontology/i
 id: GO:0009327
 name: obsolete NAD(P)+ transhydrogenase complex (AB-specific)
 namespace: cellular_component
-def: "OBSOLETE. A protein complex that possesses NAD(P)+ transhydrogenase (AB-specific) activity. Homodimeric, trimeric, and heterotetrameric complexes have been identified." [BRENDA:1.6.1.2, GOC:mah]
+def: "OBSOLETE. A protein complex that possesses NAD(P)+ transhydrogenase (AB-specific) activity. Homodimeric, trimeric, and heterotetrameric complexes have been identified." [GOC:mah]
 comment: This term was obsoleted because there is no evidence that this activity exists as part of a complex.
 is_obsolete: true
 
@@ -89709,7 +89708,7 @@ relationship: part_of GO:0005737 ! cytoplasm
 id: GO:0009337
 name: sulfite reductase complex (NADPH)
 namespace: cellular_component
-def: "A multisubunit iron flavoprotein, which in yeast is composed of 2 alpha and 2 beta subunits. Catalyzes the reduction of sulfite to sulfide." [BRENDA:1.8.1.2, GOC:jl]
+def: "A multisubunit iron flavoprotein, which in yeast is composed of 2 alpha and 2 beta subunits. Catalyzes the reduction of sulfite to sulfide." [GOC:jl, PMID:6751400]
 comment: See also the molecular function term 'sulfite reductase (NADPH) activity ; GO:0004783'.
 synonym: "sulphite reductase complex (NADPH)" EXACT []
 is_a: GO:0140535 ! intracellular protein-containing complex
@@ -108545,7 +108544,7 @@ is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorp
 id: GO:0015050
 name: methane monooxygenase complex
 namespace: cellular_component
-def: "A protein complex that possesses methane monooxygenase activity; dimeric and trimeric complexes have been characterized." [BRENDA:1.14.13.25, GOC:mah]
+def: "A protein complex that possesses methane monooxygenase activity; dimeric and trimeric complexes have been characterized." [GOC:mah, PMID:15544]
 intersection_of: GO:0032991 ! protein-containing complex
 intersection_of: capable_of GO:0015049 ! methane monooxygenase activity
 
@@ -235275,7 +235274,7 @@ intersection_of: has_primary_input CHEBI:18287 ! L-fucose
 id: GO:0042356
 name: GDP-4-dehydro-D-rhamnose reductase activity
 namespace: molecular_function
-def: "Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4 epimer is formed." [BRENDA:1.1.1.187, EC:1.1.1.187]
+def: "Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4 epimer is formed." [EC:1.1.1.187]
 synonym: "GDP-4-keto-6-deoxy-D-mannose reductase activity" RELATED [EC:1.1.1.187]
 synonym: "GDP-4-keto-D-rhamnose reductase activity" RELATED [EC:1.1.1.187]
 synonym: "GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase activity" RELATED [EC:1.1.1.187]
@@ -244358,7 +244357,7 @@ is_a: GO:0019899 ! enzyme binding
 id: GO:0043275
 name: obsolete glutamate carboxypeptidase II activity
 namespace: molecular_function
-def: "OBSOLETE. Catalysis of the reaction: N-acetyl-L-Asp-L-Glu + H2O = N-acetyl-L-Asp + L-Glu." [BRENDA:3.4.17.21, GOC:jl]
+def: "OBSOLETE. Catalysis of the reaction: N-acetyl-L-Asp-L-Glu + H2O = N-acetyl-L-Asp + L-Glu." [GOC:jl]
 comment: This term was made obsolete because it represents a gene product.
 synonym: "acetylaspartylglutamate dipeptidase activity" EXACT []
 synonym: "folate hydrolase activity" RELATED [EC:3.4.17.21]