Speos, pronounced almost like "space", is a machine learning framework to merge deep learning and the omnigenic model. Its goal is to predict core genes for several diseases which allow subsequent research to allocate resources to the most promising candidates.
For the installation instructions please see the documentation.
https://speos.readthedocs.io/en/latest/index.html
Speos has now been published in Nature Communications! https://www.nature.com/articles/s41467-023-42975-z
If you use Speos in your work, please cite the paper above. You can use the following information:
@article{ratajczak_speos_2023,
title = {Speos: an ensemble graph representation learning framework to predict core gene candidates for complex diseases},
author = {Ratajczak, Florin and Joblin, Mitchell and Hildebrandt, Marcel and Ringsquandl, Martin and Falter-Braun, Pascal and Heinig, Matthias},
journal = {Nature Communications},
volume = {14},
url = {https://www.nature.com/articles/s41467-023-42975-z},
doi = {10.1038/s41467-023-42975-z},
year = {2023},
pages = {7206}
}