GENE Platform

Gene Expression Explorer

A desktop application for gene expression analysis of bulk RNA-seq data, built with Electron and React. This project is a rewrite of the original Flask-based web application.

Features

• Exploratory Data Analysis
• Differential expression analysis for bulk RNA-seq data with a limma-voom pipeline
• Enrichment analysis via limma's camera method
• Interactive data visualization
• Load harmonized GEO and GDC datasets
• Local data processing via WebAssembly

Setup

Set up and launch GENE on your machine.

Prerequisites

• Install Git. macOS users can run git -v in Terminal for automatic installation. On Windows, download the installer from git-scm.com and perform a standard installation.
• Install Node.js. Download and run the installer from nodejs.org. You may perform a regular installation using the default options. No extra dependencies are necessary.

Install and Launch GENE

Set up and launch the app from a new command line session. Launch Command Prompt on Windows or Terminal on macOS, and run the four commands below in sequence.

1. Clone this repository.

   git clone https://github.com/fogg-lab/gene-platform.git

2. Navigate to the project root directory.

   cd gene-platform

3. Install project dependencies.

   npm install

4. Launch the app in development mode.

   npm run dev

Quickstart demo

Follow this link to watch a 5-minute demo.