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Releases: epigen/spilterlize_integrate

v2.0.1 - Enable module usage using `github()` directive

20 Dec 15:19
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  • to enable module usage using github() directive
    • comment global.yaml (now requires full snakemake installation, not minimal)
  • add nodefaults to all env YAML

Full Changelog: v2.0.0...v2.0.1

v2.0.0 - Snakemake 8 compatible

12 Sep 16:30
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Breaking change: Requires Snakemake >= v8.20.1.

Full Changelog: v1.2.0...v2.0.0

v1.2.0 - Correlation Heatmaps

10 Jul 13:27
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Features

  • Correlation Heatmaps
    • Heatmap of sample-wise Pearson correlation matrix of the respective data split and processing step to quickly assess sample similarities e.g., replicates/conditions should correlate highly but batch should not.
    • Hierarchically clustered using method 'complete' with distance metric 'euclidean'.
    • Alphabetically sorted by sample name.

Full Changelog: v1.1.0...v1.2.0

v1.1.0 - Confounding Factor Analysis

22 May 10:03
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Features

  • Confounding Factor Analysis (CFA): Added a new feature to assess and visualize the statistical associations between metadata and principal components (PCs) using Kruskal-Wallis (categorical) and Kendall's Tau (numeric) tests, with results displayed as a heatmap of -log10 adjusted p-values.
  • Added VOOM normalization-specific Mean-Variance trend plot.
  • Improved visualization of the mean-variance relationship in the diagnostic plot using hexagonal heatmaps of 2d bin counts.

Bugfixes

  • fixed reComBat pip dependency issue using Snakemake's post-deployment script functionality.

Documentation

  • Tested on ATAC-seq count data from >200 samples.
  • Tested step-wise with minimal to maximal conjugations (i.e., from splitting up to integration).
  • Added other assays that could benefit from this module to the README.
  • Updated documentation with new features.
  • Added new visualizations to the Snakemake report.

Full Changelog: v1.0.1...v1.1.0

fix CITATION.cff

13 Jul 15:08
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v1.0.1

Update CITATION.cff

stable version with all features and complete documentation