#6085 - Changing of ambiguous base via RNA Builder on Sequence mode c…

…auses sequence corruption (#6264) * feat: add logic for natural analog base * test:update test
epam · Jan 20, 2025 · 63019b4 · 63019b4
1 parent b3b6a67
commit 63019b4
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diff --git a/...A-builde-94fe3-lected-Sugar-Base-Phosphates-in-RNA-Builder-1-chromium-linux.png b/...A-builde-94fe3-lected-Sugar-Base-Phosphates-in-RNA-Builder-1-chromium-linux.png
diff --git a/...rc/components/monomerLibrary/RnaBuilder/RnaEditor/RnaEditorExpanded/RnaEditorExpanded.tsx b/...rc/components/monomerLibrary/RnaBuilder/RnaEditor/RnaEditorExpanded/RnaEditorExpanded.tsx
@@ -164,9 +164,17 @@ export const RnaEditorExpanded = ({
         const monomerType =
           monomerGroupToPresetGroup[activePresetMonomerGroup.groupName];
         const field = `${monomerType}Label`;
+
         const updatedSequenceSelection = sequenceSelection.map((node) => {
           // Do not set 'phosphateLabel' for Nucleoside if it is connected and selected with Phosphate
           // Do not set 'sugarLabel', 'baseLabel' for Phosphate
+          const naturalAnalog =
+            field === 'baseLabel' &&
+            activePresetMonomerGroup.groupItem.props?.MonomerNaturalAnalogCode
+              ? activePresetMonomerGroup.groupItem.props
+                  .MonomerNaturalAnalogCode
+              : activePresetMonomerGroup.groupItem.label;
+
           if (
             (node.isNucleosideConnectedAndSelectedWithPhosphate &&
               field === 'phosphateLabel') ||
@@ -177,9 +185,10 @@ export const RnaEditorExpanded = ({
 
           return {
             ...node,
-            [field]: activePresetMonomerGroup.groupItem.label,
+            [field]: naturalAnalog,
           };
         });
+
         setIsSequenceSelectionUpdated(true);
         dispatch(setSequenceSelection(updatedSequenceSelection));
       } else {