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# 0024_GRNCoopSW8_001 | ||
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a gene regulatory network of 100 genes connected according to a small-world topology, from the AGN suite | ||
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## tests | ||
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- 1D, 100 units, network, GRN | ||
- cps file reads well | ||
- network file reads well | ||
- named output file | ||
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- checks the regulated_by_1 rate law was created | ||
- checks that there are exactly 3 species | ||
- checks that noise worked | ||
- checks no compartments created | ||
- checks that there are three synthesis reactions |
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#!/bin/bash | ||
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# work out our folder name | ||
test=${PWD##*/} # to assign to a variable | ||
test=${test:-/} # to correct for the case where PWD=/ | ||
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# run sbmodelr | ||
../../sbmodelr -g G --cn 2 uni --grn-a -1 --grn-h 8 --grn-V 2 -n ../sources/CoopSW8_001.dot -o CoopSW8_001.cps --ignore-compartments ../sources/GeneExpressionUnit.cps 100 > output | ||
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fail=0 | ||
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# compare output and target | ||
difference=$(diff output target_stdout) | ||
if [[ $difference ]]; then | ||
printf 'FAIL %s\n' "${test}" | ||
fail=1 | ||
fi | ||
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# create model summary | ||
../model_report.py CoopSW8_001.cps >/dev/null | ||
if ! [[ $? = 0 ]]; then | ||
printf 'FAIL %s\n' "${test}" | ||
exit -1 | ||
fi | ||
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# check that there is one rate law for regulation by 2 | ||
if ! grep -Pq "^regulated_by_2\s+V \* \( \( 1 \+ \( 1 \+ a1 \) \* M1 \^ h1 \) \/ \( 1 \+ M1 \^ h1 \) \) \* \( \( 1 \+ \( 1 \+ a2 \) \* M2 \^ h2 \) \/ \( 1 \+ M2 \^ h2 \) \)" CoopSW8_001.summary.txt; then | ||
printf 'FAIL %s\n' "${test}" | ||
let "fail = $fail + 2" | ||
fi | ||
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# check that there are 100 species | ||
n=$(grep -Pc "^G_\d+\s+reactions\s+\d+\.\d+" CoopSW8_001.summary.txt) | ||
if ((n != 100)); then | ||
printf 'FAIL %s\n' "${test}" | ||
let "fail = $fail + 4" | ||
fi | ||
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exit $fail | ||
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# check that min and max of initial concentrations are different (meaning noise worked!) | ||
n=$(grep -Po "^G_[123]\s+reactions\s+([0-9]+\.[0-9]+\s)" repressilator.summary.txt | awk '(NR==1){Min=$3;Max=$3};(NR>=2){if(Min>$3) Min=$3;if(Max<$3) Max=$3} END {if(Min<Max) {print 0} else {print 1}}') | ||
if ((n != 0)) ; then | ||
printf 'FAIL %s\n' "${test}" | ||
let "fail = $fail + 8" | ||
fi | ||
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# check that no new compartments were created | ||
n=$(grep -Pc "^cell_[123]\s+fixed" repressilator.summary.txt) | ||
if ((n != 0)) ; then | ||
printf 'FAIL %s\n' "${test}" | ||
let "fail = $fail + 16" | ||
fi | ||
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# checks that there are three synthesis reactions | ||
n=$(grep -Pc "synthesis (G_[123])\s+-> \1\;\s+G_[123]\s+regulated_by_1" repressilator.summary.txt) | ||
if ((n != 3)) ; then | ||
printf 'FAIL %s\n' "${test}" | ||
let "fail = $fail + 32" | ||
fi | ||
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if [ "$fail" = 0 ] ; then | ||
printf 'PASS %s\n' "${test}" | ||
rm repressilator.summary.txt output *.cps | ||
fi | ||
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exit $fail |
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Processing ../sources/GeneExpressionUnit.cps | ||
Reactions: 2 | ||
Species: 1 (Reactions: 1, Fixed: 0, Assignment: 0, ODE: 0) | ||
Compartments: 1 (Fixed: 1, Assignment: 0, ODE: 0) | ||
Global quantities: 0 (Fixed: 0, Assignment: 0, ODE: 0) | ||
Events: 0 (Only time-dependent: 0, variable-dependent: 0) | ||
Network: directed (Nodes: 100, Edges: 200) | ||
created new model CoopSW8_001.cps with a set of 100 replicas of ../sources/GeneExpressionUnit.cps | ||
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