quantgen

code based on Quantitative Genetics (Caballero A. 2020)

based on chance, should be used for entertainment only and should not be used for investment purposes

stochastic 2-allele mutation/selection/drift/migration model

model.py: stochastic 2-allele frequency dynamics

input:

initial population parameters

--p initial observed frequency of allele A1 (defaults to 1 heterozygous individual unless otherwise specified)

--N population size (default = 10000)

--t number of generations (default = 100)

--reps number of replicate populations (default = 10)

--s selection coefficient (default = 0)

--h heterozygous effect (default = 0)

--m probability of migration (assumes immigration of individuals homozygous for allele A2, random emigration, default = 0)

--u probability of mutation (default = 2 * 10e-8)

--out output (appended with .png, .txt)

output:

plot of allele frequency over generations, .tsv tracking allele frequency across replicates over generations

example: drift

  python model.py --out test --N 100 --p 0.5 --out test