Version 1.0.2

2020-03-17

Front End

• Update dependencies
• Add correct DOI (10.1038/s41467-019-12829-8)
• Fix some rel attributes on links

Server and API

• Update dependencies

Version 1.0.1

2019-12-09

Changes:

• Update dependencies (fixing a vulnerability in serialize-javascript)

Version 1.0.0

2019-09-24

Final release version for publication. Incorporates changes from initial submission as well (listed separately).

Since Initial Submission:

Front End

• Update dependencies
• Document functions
• Update tooltip text
• Revise layout
• Show cartoons in table instead of modal
• Set default min_mh_1l to 3
• Improve display by grouping columns
  • Allows expanding/collapsing and hidden columns
• Add inDelphi scores, bar charts
• Fix some small user interface issues
• Fix ClinVar URLs linking to the wrong variants
• Fix loading forever when no results are found
• Add "no results" message
• Improve loading performance
• Add terms and conditions
• Add bug reporting form

Server and API

• Update dependencies
• Fix GC content in variants endpoint
• Add bug reporting support
• Add inDelphi scores

Database

• Add bug reporting support
• Add inDelphi scores

Miscellaneous

• Add LICENSE

Prior to Initial Submission:

Front End

• Update dependencies
• Fix some small user interface issues
• Remove dbSNP checkbox
• Add "developed by CiRA / C3G"

Server and API

• Update dependencies
• Use min_mh_1l instead of min_mh_l for queries
• Make some string search operations case insensitive

Database

• Update schema to support new TSV format

Miscellaneous

• Update documentation
• Clean up some vestigial stuff

Version 0.4.0

2018-08-23

Renamed once again, this time to "MHcut Browser".

Front End

• Allow keyboard submission of filtering and searching form.
• Allow the user to escape modals with the escape key.
• Add instructions on using the advanced search feature.
• Add an export modal window for exporting variant, guide, and combined
  search results as TSV files.
• Fix some quick filters not resetting properly.
• Add quick filters for "NGG PAM avail."/"Unique guide avail."
• Add tab for viewing guides that relate to the currently-loaded set of
  variants.
• Add modal table for viewing a specific variant's guides.
• Add a non-sortable column for viewing variant cartoons.
• Add tooltips for variant table columns.
• Fix column formatting for PMC citations.
• Made several changes to aid performance with the complete data-set.

Server and API

• Add endpoint for exporting TSV-formatted variant, guide, and combined
  search results.
• Add filtering support for "NGG PAM avail."/"Unique guide avail."
• Add endpoints for viewing guides.
• Include cartoons in variants endpoint.
• Made several querying changes to aid performance with the complete
  data-set.

Database

• Moved to PostgreSQL.
• Schema now includes tables for guides, cartoons, key-value metadata, and
  cached counts.
• tsv_to_postgres.py now takes in additional arguments for guides and
  cartoons files, as well as database name and user; it now adds these values
  to the database and pre-computes some metadata.
• Made several schema changes to aid performance with the complete data-set.

Version 0.3.1

2018-08-02

Server and API

• Fix issue with loading version number in production.

Version 0.3.0

2018-08-02

Front End

• Logo added to sidebar.
• Sidebar width increased and layout changed for increased vertical space.
• Fix status text showing 0 total pages if no results were found.
• Remove "Position Filter Type" quick filter option (by request).
• Add "Minimum mhL" and "Database Sources" quick filter options (by request).

Server and API

• NA now treated internally as NULL for the gene_info_clinvar database
  column.
• Add application version to metadata endpoint.
• Add min_mh_l (minimum mhL value), dbsnp (must an entry be in dbSNP?),
  and clinvar (must an entry be in ClinVar?) search parameters.

Miscellaneous

• tsv_to_sqlite.py now accepts a mandatory argument for the TSV file
  instead of always using variants-subset.tsv.
• uWSGI ini file and example systemd service files are now available.

Version 0.2.0

2018-07-31

Front End

• Name changed to "CRISPR Cut Browser".
• Citations now link to their respective pages on NCBI PubMed / Bookshelf.
• Entries in the gene_info_clinvar now also link to NCBI Gene entries.

Version 0.1.0

2018-07-30

Initial release.