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t-sne on binary regulon activity #598

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robertzeibich opened this issue Jan 9, 2025 · 0 comments
Open

t-sne on binary regulon activity #598

robertzeibich opened this issue Jan 9, 2025 · 0 comments
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@robertzeibich
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I am wondering how plot d was generated.

I was thinking of the following:

#binary_mtx
binary_mtx, auc_thresholds = binarize(auc_mtx, num_workers=24)
adata.obsm['X_aucell_bin'] = np.array(binary_mtx)
sc.tl.tsne(adata, use_rep='X_aucell_bin')
adata.obsm['X_tsne_aucell_bin'] = adata.obsm.pop('X_tsne')

However, I saw that each cell type had the extension GRN.

@robertzeibich robertzeibich added the question Further information is requested label Jan 9, 2025
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