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ZHBHSMILE · Aug 27, 2024 · 9146765 · 9146765
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diff --git a/2024/08/26/DIANN/index.html b/2024/08/26/DIANN/index.html
@@ -87,7 +87,7 @@ <h1 class="article-title sea-center" style="border-left:0" itemprop="name">
         <span class="post-meta-item-icon">
             <i class="ri-quill-pen-line"></i>
             <span class="post-meta-item-text"> Word count:</span>
-            <span class="post-count">7k</span>
+            <span class="post-count">6.9k</span>
         </span>
     </span>
 
@@ -113,23 +113,18 @@ <h1 class="article-title sea-center" style="border-left:0" itemprop="name">
 
   <p><a target="_blank" rel="noopener" href="http://music.163.com/#/song?id=2145149147">http://music.163.com/#/song?id=2145149147</a></p>
 
-    <div id="aplayer-MejXoXCQ" class="aplayer aplayer-tag-marker meting-tag-marker"
+    <div id="aplayer-HEkVZTVq" class="aplayer aplayer-tag-marker meting-tag-marker"
          data-id="468176711" data-server="netease" data-type="song" data-mode="circulation" data-autoplay="false" data-mutex="true" data-listmaxheight="340px" data-preload="auto" data-theme="#ad7a86"
     ></div>
 <!-- 
-    <div id="aplayer-whavVTxp" class="aplayer aplayer-tag-marker meting-tag-marker"
+    <div id="aplayer-bndwNplV" class="aplayer aplayer-tag-marker meting-tag-marker"
          data-id="002j785c33YQHT" data-server="tencent" data-type="song" data-mode="circulation" data-autoplay="false" data-mutex="true" data-listmaxheight="340px" data-preload="auto" data-theme="#ad7a86"
     ></div> -->
 <!-- 
-    <div id="aplayer-XXSuKhQS" class="aplayer aplayer-tag-marker meting-tag-marker"
+    <div id="aplayer-ZtbTyFWt" class="aplayer aplayer-tag-marker meting-tag-marker"
          data-id="001Mf4Ic1aNYYK" data-server="tencent" data-type="album" data-mode="circulation" data-autoplay="false" data-mutex="true" data-listmaxheight="180px" data-preload="auto" data-theme="#ad7a86" data-order="random"
     ></div> -->
-<ol>
-<li>Spectral:谱图</li>
-</ol>
-<blockquote>
-<p>the library must <strong>not</strong> contain <strong>non-fragmented precursor ions</strong> as ‘fragments’<br> precursor。each fragment ion must actually be produced by the peptide backbone fragmentation.：在质谱分析中，前体离子通常指的是在质谱仪中经过某种方式（如电离）产生的、尚未进一步碎裂的离子。这些离子在质谱仪的进一步处理中（如碰撞诱导解离CID、高能碰撞解离HCD等）可能会被碎裂成更小的片段离子（Fragment Ions），这些片段离子随后被用于化合物的鉴定和结构分析。</p>
-</blockquote>
+<p>$S&#x3D;\sqrt{\frac{\sum{(X-\bar{X})^2}} {n-1}}$</p>
 <h3 id="为什么进行FASTA文件消化？"><a href="#为什么进行FASTA文件消化？" class="headerlink" title="为什么进行FASTA文件消化？"></a>为什么进行FASTA文件消化？</h3><p><strong>不依赖谱库的搜索（library-free search）方法</strong>，如DIA-NN，直接使用FASTA文件中的蛋白质序列生成假设的肽段，并通过这些<strong>肽段来匹配实验数据</strong>。这种方法<strong>不需要预先构建的谱库，</strong>使得分析过程更加灵活和广泛适用，特别是对于未研究过的样本或新发现的蛋白质。</p>
 <h3 id="DIA-NN中的FASTA文件消化步骤"><a href="#DIA-NN中的FASTA文件消化步骤" class="headerlink" title="DIA-NN中的FASTA文件消化步骤"></a>DIA-NN中的FASTA文件消化步骤</h3><ol>
 <li><strong>加载FASTA文件</strong>: 研究人员将包含目标蛋白质序列的FASTA文件输入到DIA-NN中。</li>
@@ -877,6 +872,11 @@ <h3 id="Summary"><a href="#Summary" class="headerlink" title="Summary"></a>Summa
 <script src="https://cdn.jsdelivr.net/npm/meting@2/dist/Meting.min.js"></script>
 
 
+<link(rel='stylesheet' href=url_for(theme.asset.aplayer_css) media="print" onload="this.media='all'")
+script(src=url_for(theme.asset.aplayer_js))
+script(src=url_for(theme.asset.meting_js))
++script.
++  var meting_api='https://zhao-peng.top/api/?server=:server&type=:type&id=:id&auth=:auth&r=:r';</ink>
 
 
 

diff --git a/about/index.html b/about/index.html
@@ -522,6 +522,11 @@ <h1 class="article-title sea-center" style="border-left:0" itemprop="name">
 <script src="https://cdn.jsdelivr.net/npm/meting@2/dist/Meting.min.js"></script>
 
 
+<link(rel='stylesheet' href=url_for(theme.asset.aplayer_css) media="print" onload="this.media='all'")
+script(src=url_for(theme.asset.aplayer_js))
+script(src=url_for(theme.asset.meting_js))
++script.
++  var meting_api='https://zhao-peng.top/api/?server=:server&type=:type&id=:id&auth=:auth&r=:r';</ink>
 
 
 

diff --git a/archives/2024/08/index.html b/archives/2024/08/index.html
@@ -439,6 +439,11 @@ <h2 itemprop="name">
 <script src="https://cdn.jsdelivr.net/npm/meting@2/dist/Meting.min.js"></script>
 
 
+<link(rel='stylesheet' href=url_for(theme.asset.aplayer_css) media="print" onload="this.media='all'")
+script(src=url_for(theme.asset.aplayer_js))
+script(src=url_for(theme.asset.meting_js))
++script.
++  var meting_api='https://zhao-peng.top/api/?server=:server&type=:type&id=:id&auth=:auth&r=:r';</ink>
 
 
 

diff --git a/archives/2024/index.html b/archives/2024/index.html
@@ -439,6 +439,11 @@ <h2 itemprop="name">
 <script src="https://cdn.jsdelivr.net/npm/meting@2/dist/Meting.min.js"></script>
 
 
+<link(rel='stylesheet' href=url_for(theme.asset.aplayer_css) media="print" onload="this.media='all'")
+script(src=url_for(theme.asset.aplayer_js))
+script(src=url_for(theme.asset.meting_js))
++script.
++  var meting_api='https://zhao-peng.top/api/?server=:server&type=:type&id=:id&auth=:auth&r=:r';</ink>
 
 
 

diff --git a/archives/index.html b/archives/index.html
@@ -439,6 +439,11 @@ <h2 itemprop="name">
 <script src="https://cdn.jsdelivr.net/npm/meting@2/dist/Meting.min.js"></script>
 
 
+<link(rel='stylesheet' href=url_for(theme.asset.aplayer_css) media="print" onload="this.media='all'")
+script(src=url_for(theme.asset.aplayer_js))
+script(src=url_for(theme.asset.meting_js))
++script.
++  var meting_api='https://zhao-peng.top/api/?server=:server&type=:type&id=:id&auth=:auth&r=:r';</ink>
 
 
 

diff --git a/categories/index.html b/categories/index.html
@@ -399,6 +399,11 @@ <h1 class="page-type-title">Categories</h1>
 <script src="https://cdn.jsdelivr.net/npm/meting@2/dist/Meting.min.js"></script>
 
 
+<link(rel='stylesheet' href=url_for(theme.asset.aplayer_css) media="print" onload="this.media='all'")
+script(src=url_for(theme.asset.aplayer_js))
+script(src=url_for(theme.asset.meting_js))
++script.
++  var meting_api='https://zhao-peng.top/api/?server=:server&type=:type&id=:id&auth=:auth&r=:r';</ink>
 
 
 

diff --git a/categories/蛋白/index.html b/categories/蛋白/index.html
@@ -445,6 +445,11 @@ <h2 itemprop="name">
 <script src="https://cdn.jsdelivr.net/npm/meting@2/dist/Meting.min.js"></script>
 
 
+<link(rel='stylesheet' href=url_for(theme.asset.aplayer_css) media="print" onload="this.media='all'")
+script(src=url_for(theme.asset.aplayer_js))
+script(src=url_for(theme.asset.meting_js))
++script.
++  var meting_api='https://zhao-peng.top/api/?server=:server&type=:type&id=:id&auth=:auth&r=:r';</ink>
 
 
 

diff --git a/friends/index.html b/friends/index.html
@@ -419,6 +419,11 @@ <h1 class="page-type-title">Friends</h1>
 <script src="https://cdn.jsdelivr.net/npm/meting@2/dist/Meting.min.js"></script>
 
 
+<link(rel='stylesheet' href=url_for(theme.asset.aplayer_css) media="print" onload="this.media='all'")
+script(src=url_for(theme.asset.aplayer_js))
+script(src=url_for(theme.asset.meting_js))
++script.
++  var meting_api='https://zhao-peng.top/api/?server=:server&type=:type&id=:id&auth=:auth&r=:r';</ink>
 
 
 

diff --git a/index.html b/index.html
@@ -546,6 +546,11 @@ <h2 itemprop="name">
 <script src="https://cdn.jsdelivr.net/npm/meting@2/dist/Meting.min.js"></script>
 
 
+<link(rel='stylesheet' href=url_for(theme.asset.aplayer_css) media="print" onload="this.media='all'")
+script(src=url_for(theme.asset.aplayer_js))
+script(src=url_for(theme.asset.meting_js))
++script.
++  var meting_api='https://zhao-peng.top/api/?server=:server&type=:type&id=:id&auth=:auth&r=:r';</ink>
 
 
 

diff --git a/search.xml b/search.xml
@@ -5,23 +5,18 @@
     <url>/2024/08/26/DIANN/</url>
     <content><![CDATA[<link rel="stylesheet" class="aplayer-secondary-style-marker" href="\assets\css\APlayer.min.css"><script src="\assets\js\APlayer.min.js" class="aplayer-secondary-script-marker"></script><script class="meting-secondary-script-marker" src="\assets\js\Meting.min.js"></script><p><a href="http://music.163.com/#/song?id=2145149147">http://music.163.com/#/song?id=2145149147</a></p>
 
-    <div id="aplayer-MejXoXCQ" class="aplayer aplayer-tag-marker meting-tag-marker"
+    <div id="aplayer-HEkVZTVq" class="aplayer aplayer-tag-marker meting-tag-marker"
          data-id="468176711" data-server="netease" data-type="song" data-mode="circulation" data-autoplay="false" data-mutex="true" data-listmaxheight="340px" data-preload="auto" data-theme="#ad7a86"
     ></div>
 <!-- 
-    <div id="aplayer-whavVTxp" class="aplayer aplayer-tag-marker meting-tag-marker"
+    <div id="aplayer-bndwNplV" class="aplayer aplayer-tag-marker meting-tag-marker"
          data-id="002j785c33YQHT" data-server="tencent" data-type="song" data-mode="circulation" data-autoplay="false" data-mutex="true" data-listmaxheight="340px" data-preload="auto" data-theme="#ad7a86"
     ></div> -->
 <!-- 
-    <div id="aplayer-XXSuKhQS" class="aplayer aplayer-tag-marker meting-tag-marker"
+    <div id="aplayer-ZtbTyFWt" class="aplayer aplayer-tag-marker meting-tag-marker"
          data-id="001Mf4Ic1aNYYK" data-server="tencent" data-type="album" data-mode="circulation" data-autoplay="false" data-mutex="true" data-listmaxheight="180px" data-preload="auto" data-theme="#ad7a86" data-order="random"
     ></div> -->
-<ol>
-<li>Spectral:谱图</li>
-</ol>
-<blockquote>
-<p>the library must <strong>not</strong> contain <strong>non-fragmented precursor ions</strong> as ‘fragments’<br> precursor。each fragment ion must actually be produced by the peptide backbone fragmentation.：在质谱分析中，前体离子通常指的是在质谱仪中经过某种方式（如电离）产生的、尚未进一步碎裂的离子。这些离子在质谱仪的进一步处理中（如碰撞诱导解离CID、高能碰撞解离HCD等）可能会被碎裂成更小的片段离子（Fragment Ions），这些片段离子随后被用于化合物的鉴定和结构分析。</p>
-</blockquote>
+<p>$S&#x3D;\sqrt{\frac{\sum{(X-\bar{X})^2}} {n-1}}$</p>
 <h3 id="为什么进行FASTA文件消化？"><a href="#为什么进行FASTA文件消化？" class="headerlink" title="为什么进行FASTA文件消化？"></a>为什么进行FASTA文件消化？</h3><p><strong>不依赖谱库的搜索（library-free search）方法</strong>，如DIA-NN，直接使用FASTA文件中的蛋白质序列生成假设的肽段，并通过这些<strong>肽段来匹配实验数据</strong>。这种方法<strong>不需要预先构建的谱库，</strong>使得分析过程更加灵活和广泛适用，特别是对于未研究过的样本或新发现的蛋白质。</p>
 <h3 id="DIA-NN中的FASTA文件消化步骤"><a href="#DIA-NN中的FASTA文件消化步骤" class="headerlink" title="DIA-NN中的FASTA文件消化步骤"></a>DIA-NN中的FASTA文件消化步骤</h3><ol>
 <li><strong>加载FASTA文件</strong>: 研究人员将包含目标蛋白质序列的FASTA文件输入到DIA-NN中。</li>

diff --git a/tags/DIA-NN/index.html b/tags/DIA-NN/index.html
@@ -443,6 +443,11 @@ <h2 itemprop="name">
 <script src="https://cdn.jsdelivr.net/npm/meting@2/dist/Meting.min.js"></script>
 
 
+<link(rel='stylesheet' href=url_for(theme.asset.aplayer_css) media="print" onload="this.media='all'")
+script(src=url_for(theme.asset.aplayer_js))
+script(src=url_for(theme.asset.meting_js))
++script.
++  var meting_api='https://zhao-peng.top/api/?server=:server&type=:type&id=:id&auth=:auth&r=:r';</ink>
 
 
 

diff --git a/tags/index.html b/tags/index.html
@@ -399,6 +399,11 @@ <h1 class="page-type-title">Tags</h1>
 <script src="https://cdn.jsdelivr.net/npm/meting@2/dist/Meting.min.js"></script>
 
 
+<link(rel='stylesheet' href=url_for(theme.asset.aplayer_css) media="print" onload="this.media='all'")
+script(src=url_for(theme.asset.aplayer_js))
+script(src=url_for(theme.asset.meting_js))
++script.
++  var meting_api='https://zhao-peng.top/api/?server=:server&type=:type&id=:id&auth=:auth&r=:r';</ink>