AD_QSP_model.py
This code includes simulation of baseline levels of biological facotors, %improved EASI, and EASI-75 when placebo or drugs were applied
Miyano T, Irvine AD, Tanaka RJ. A mathematical model to identify optimal combinations of drug targets for dupilumab poor responders in atopic dermatitis. Allergy. 2021;10.1111/all.14870. doi:10.1111/all.14870
Distribution parameters
mu : mu.csv
sigma : sigma.csv
These values were used in the publication
QSP_model_of_Saureus_targeted-therapy.py
This code includes simulation of baseline levels of biological facotors, %improved EASI, EASI-75 and other biological factors when placebo or drugs were applied
Distribution parameters
mu : mu_Saureus.csv
sigma : sigma_Saureus.csv
These values were used in the publication