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updated pedaitrics.csv (#77)
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* Update Pediatrics.csv

corrected clearance value ratnapalan ID 4

* converted units for ratnapalan et al, and corrected units nyberg et al.

* adjusted units

* Saved as UTF-8

* removed  symbols that occured after saving

* adjusted comment
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Ibrahim Ince authored Feb 15, 2023
1 parent db1d4e4 commit 75ea83b
Showing 1 changed file with 21 additions and 21 deletions.
42 changes: 21 additions & 21 deletions Pediatrics.csv
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ID,Study,Reference,Grouping,Analyte,t0,tend,t Unit,AUC Avg,AUC AvgUnit,AUC AvgType,AUC Var,AUC VarUnit,AUC VarType,AUC Type,Cmax Avg,Cmax AvgUnit,Cmax AvgType,Cmax Var,Cmax VarUnit,Cmax VarType,Cmax Type,CL Avg,CL AvgUnit,CL AvgType,CL Var,CL VarUnit,CL VarType,CL Type,Comment
ID,Study,Reference,Grouping,Analyte,t0,tend,t Unit,AUC Avg,AUC AvgUnit,AUC AvgType,AUC Var,AUC VarUnit,AUC VarType,AUC Type,Cmax Avg,Cmax AvgUnit,Cmax AvgType,Cmax Var,Cmax VarUnit,Cmax VarType,Cmax Type,CL Avg,CL AvgUnit,CL AvgType,CL Var,CL VarUnit,CL VarType,CL Type,Comment
5127,Bovill 1984,https://www.ncbi.nlm.nih.gov/pubmed/6238552,mean,Sufentanil,0,8,h,,,,,,,,,,,,,,,12.66,mL/min/kg,arith. Mean,0.78,mL/kg/min,arith. SEM,CLiv,Table 3
5128,Willsie 2015,https://www.ncbi.nlm.nih.gov/pubmed/25544247,mean,Sufentanil,0,1440,min,273.8,pg*h/mL,arith. Mean,61.1,pg*h/mL,arith. SD,AUC_inf,,,,,,,,,,,,,,CLiv,
5129,Davis 1987,https://www.ncbi.nlm.nih.gov/pubmed/2950809,mean,Sufentanil,0,120,min,0.000545455,mg*min/mL,arith. Mean,,,,AUC_tau,,,,,,,,27.5,mL/min/kg,arith. Mean,9.3,mL/kg/min,arith. Mean,CLiv,"Table 3, last samples taken 120 OR until the initiation of cardiopulmonary bypass, AUCinf imputed based on reported Dose/CL"
Expand Down Expand Up @@ -256,23 +256,23 @@ ID,Study,Reference,Grouping,Analyte,t0,tend,t Unit,AUC Avg,AUC AvgUnit,AUC AvgTy
5201,Rane 1976,https://www.ncbi.nlm.nih.gov/pubmed/1017153,3-9d,Digoxin,0,24,h,,,,,,,,,,,,,,,1.8,mL/min/kg,arith. Mean,,,,,
5202,Rane 1976,https://www.ncbi.nlm.nih.gov/pubmed/1017153,1.3-11m,Digoxin,0,24,h,,,,,,,,,,,,,,,7.5,mL/min/kg,arith. Mean,,,,,
5203,Rane 1976,https://www.ncbi.nlm.nih.gov/pubmed/1017153,2-5y,Digoxin,0,24,h,,,,,,,,,,,,,,,11.1,mL/min/kg,arith. Mean,,,,,
5204,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID1,Digoxin,0,24,h,,,,,,,,,,,,,,,105.6,mL/min/m2,Individual,,,,,
5205,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID2,Digoxin,0,24,h,,,,,,,,,,,,,,,62.1,mL/min/m2,Individual,,,,,
5206,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID3,Digoxin,0,24,h,,,,,,,,,,,,,,,98.4,mL/min/m2,Individual,,,,,
5207,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID4,Digoxin,0,24,h,,,,,,,,,,,,,,,63.6,mL/min/m2,Individual,,,,,
5208,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID5,Digoxin,0,24,h,,,,,,,,,,,,,,,202.3,mL/min/m2,Individual,,,,,
5209,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID6,Digoxin,0,24,h,,,,,,,,,,,,,,,117.8,mL/min/m2,Individual,,,,,
5210,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID7,Digoxin,0,24,h,,,,,,,,,,,,,,,353,mL/min/m2,Individual,,,,,
5211,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID8,Digoxin,0,24,h,,,,,,,,,,,,,,,74.08,mL/min/m2,Individual,,,,,
5212,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID9,Digoxin,0,24,h,,,,,,,,,,,,,,,94.4,mL/min/m2,Individual,,,,,
5213,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID10,Digoxin,0,24,h,,,,,,,,,,,,,,,107.8,mL/min/m2,Individual,,,,,
5214,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID11,Digoxin,0,24,h,,,,,,,,,,,,,,,63.7,mL/min/m2,Individual,,,,,
5215,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID12,Digoxin,0,24,h,,,,,,,,,,,,,,,56.1,mL/min/m2,Individual,,,,,
5216,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID13,Digoxin,0,24,h,,,,,,,,,,,,,,,100,mL/min/m2,Individual,,,,,
5217,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID14,Digoxin,0,24,h,,,,,,,,,,,,,,,65.1,mL/min/m2,Individual,,,,,
5218,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID15,Digoxin,0,24,h,,,,,,,,,,,,,,,132.8,mL/min/m2,Individual,,,,,
5219,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID16,Digoxin,0,24,h,,,,,,,,,,,,,,,62.5,mL/min/m2,Individual,,,,,
5220,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID17,Digoxin,0,24,h,,,,,,,,,,,,,,,172.3,mL/min/m2,Individual,,,,,
5221,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID18,Digoxin,0,24,h,,,,,,,,,,,,,,,98.7,mL/min/m2,Individual,,,,,
5222,Nyberg 1980,https://www.ncbi.nlm.nih.gov/pubmed/7398751,neonates,Digoxin,0,24,h,,,,,,,,,,,,,,,3,mL/min/1.73m2,arith. Mean,,,,,Taken from Nyber 1978 reported doses and serum concentrations
5223,Nyberg 1980,https://www.ncbi.nlm.nih.gov/pubmed/7398751,infants (moderate cl),Digoxin,0,24,h,,,,,,,,,,,,,,,4.5,mL/min/1.73m2,arith. Mean,,,,,Taken from Nyber 1978 reported doses and serum concentrations
5204,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID1-1y,Digoxin,0,24,h,,,,,,,,,,,,,,,3.9072,mL/min/kg,Individual,,,,,Clearance converted from mL/min/m2 to mL/min/kg using reported m2 values and PK-sim generated BW according to the given age
5205,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID1-DDI 15m,Digoxin,0,24,h,,,,,,,,,,,,,,,2.293465909,mL/min/kg,Individual,,,,,Clearance converted from mL/min/m2 to mL/min/kg using reported m2 values and PK-sim generated BW according to the given age
5206,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID1-16m,Digoxin,0,24,h,,,,,,,,,,,,,,,3.661395349,mL/min/kg,Individual,,,,,Clearance converted from mL/min/m2 to mL/min/kg using reported m2 values and PK-sim generated BW according to the given age
5207,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,"ID1-DDI 2y,4m",Digoxin,0,24,h,,,,,,,,,,,,,,,2.132307692,mL/min/kg,Individual,,,,,Clearance converted from mL/min/m2 to mL/min/kg using reported m2 values and PK-sim generated BW according to the given age
5208,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID2-9m,Digoxin,0,24,h,,,,,,,,,,,,,,,5.793794749,mL/min/kg,Individual,,,,,Clearance converted from mL/min/m2 to mL/min/kg using reported m2 values and PK-sim generated BW according to the given age
5209,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID2-DDI 13m,Digoxin,0,24,h,,,,,,,,,,,,,,,3.583709519,mL/min/kg,Individual,,,,,Clearance converted from mL/min/m2 to mL/min/kg using reported m2 values and PK-sim generated BW according to the given age
5210,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID3- 3y8m,Digoxin,0,24,h,,,,,,,,,,,,,,,13.67875,mL/min/kg,Individual,,,,,Clearance converted from mL/min/m2 to mL/min/kg using reported m2 values and PK-sim generated BW according to the given age
5211,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID3-DDI 7y8m,Digoxin,0,24,h,,,,,,,,,,,,,,,2.685507135,mL/min/kg,Individual,,,,,Clearance converted from mL/min/m2 to mL/min/kg using reported m2 values and PK-sim generated BW according to the given age
5212,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,"ID4-1y,7m",Digoxin,0,24,h,,,,,,,,,,,,,,,3.75596817,mL/min/kg,Individual,,,,,Clearance converted from mL/min/m2 to mL/min/kg using reported m2 values and PK-sim generated BW according to the given age
5213,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID4-DDI 3y5m,Digoxin,0,24,h,,,,,,,,,,,,,,,3.979663212,mL/min/kg,Individual,,,,,Clearance converted from mL/min/m2 to mL/min/kg using reported m2 values and PK-sim generated BW according to the given age
5214,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID5-2w,Digoxin,0,24,h,,,,,,,,,,,,,,,3.906933333,mL/min/kg,Individual,,,,,Clearance converted from mL/min/m2 to mL/min/kg using reported m2 values and PK-sim generated BW according to the given age
5215,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID5-DDI 4w,Digoxin,0,24,h,,,,,,,,,,,,,,,3.366,mL/min/kg,Individual,,,,,Clearance converted from mL/min/m2 to mL/min/kg using reported m2 values and PK-sim generated BW according to the given age
5216,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID6-6m,Digoxin,0,24,h,,,,,,,,,,,,,,,3.851851852,mL/min/kg,Individual,,,,,Clearance converted from mL/min/m2 to mL/min/kg using reported m2 values and PK-sim generated BW according to the given age
5217,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID6-DDI 8m,Digoxin,0,24,h,,,,,,,,,,,,,,,2.411111111,mL/min/kg,Individual,,,,,Clearance converted from mL/min/m2 to mL/min/kg using reported m2 values and PK-sim generated BW according to the given age
5218,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID7-8m,Digoxin,0,24,h,,,,,,,,,,,,,,,5.93614304,mL/min/kg,Individual,,,,,Clearance converted from mL/min/m2 to mL/min/kg using reported m2 values and PK-sim generated BW according to the given age
5219,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID7-DDI 9m,Digoxin,0,24,h,,,,,,,,,,,,,,,2.610381862,mL/min/kg,Individual,,,,,Clearance converted from mL/min/m2 to mL/min/kg using reported m2 values and PK-sim generated BW according to the given age
5220,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID8-DDI 7m,Digoxin,0,24,h,,,,,,,,,,,,,,,8.508641975,mL/min/kg,Individual,,,,,Clearance converted from mL/min/m2 to mL/min/kg using reported m2 values and PK-sim generated BW according to the given age
5221,Ratnapalan 2003,https://www.ncbi.nlm.nih.gov/pubmed/12756393,ID8-DDI 8m,Digoxin,0,24,h,,,,,,,,,,,,,,,4.537931034,mL/min/kg,Individual,,,,,Clearance converted from mL/min/m2 to mL/min/kg using reported m2 values and PK-sim generated BW according to the given age
5222,Nyberg 1980,https://www.ncbi.nlm.nih.gov/pubmed/7398751,neonates,Digoxin,0,24,h,,,,,,,,,,,,,,,3,mL/min/kg,arith. Mean,,,,,Taken from Nyber 1978 reported doses and serum concentrations
5223,Nyberg 1980,https://www.ncbi.nlm.nih.gov/pubmed/7398751,infants (moderate cl),Digoxin,0,24,h,,,,,,,,,,,,,,,4.5,mL/min/kg,arith. Mean,,,,,Taken from Nyber 1978 reported doses and serum concentrations

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