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MarkDuplicates Rust

  • A Rust porting version of Picard MarkDuplicates
  • Made for testing there is any performance benefit when writing it with Rust.

🔭 This is under development.

  • Currently implemented up to writing output bam.
  • Metrics writing code should be written.

🐃 Interim results

I tested performance with NA12878.mapped.bam, I was a bit disappointed with the results.

MarkDuplicates actually consumed most of time(About 70%) to write bam.
With 1 thread, rust-htslib and htsjdk have almost the same speed for writing bam.

Finding duplicates of rust implementation was about 1.6x faster than java(original Markduplicates), but this took up only a small fraction of the total running time.

Using 4 or 8 threads for writing and reading bam, rust implementation was much faster than java (11min, 8min vs 29min) but if htsjdk support multiple thread for writing and reading bam, I think the performance benefit may be little.

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