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genemania web
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veroniquevoisin committed Jun 17, 2024
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14 changes: 6 additions & 8 deletions 5.2-Module5_genenmania_web_lab.Rmd
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Expand Up @@ -138,7 +138,7 @@ The top functions predicted by GeneMANIA for GRN were related to lysosome and va

### Exercise 1 - STEP 11 (save an image)

<img src="./Module6/genemania/images/GM10.png" alt="start" width="60%" />
<img src="./Module6/genemania/images/GM35_2.png" alt="start" width="60%" />


**Notes** about biological interpretation of the results:
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<img src="./Module6/genemania/images/GM29.png" alt="start" width="60%" />

### Exercise 3 - STEP 4
### Exercise 3 - STEP 4/ STEP5

<img src="./Module6/genemania/images/GM30.png" alt="start" width="60%" />

### Exercise 3 - STEP 5

<img src="./Module6/genemania/images/GM31.png" alt="start" width="60%" />
<img src="./Module6/genemania/images/GM31_v2.png" alt="start" width="60%" />

### Exercise 3 - STEPS 6

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### Exercise 3 - STEP 8

<img src="./Module6/genemania/images/GM35.png" alt="start" width="60%" />
<img src="./Module6/genemania/images/GM35_2.png" alt="start" width="60%" />



<img src="./Module6/genemania/images/GM36.png" alt="start" width="60%" />

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6 changes: 3 additions & 3 deletions docs/genemania_web.html
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Expand Up @@ -762,7 +762,7 @@ <h4>Force directed layout<a href="genemania_web.html#force-directed-layout" clas
</div>
<div id="exercise-1---step-11-save-an-image" class="section level3 hasAnchor">
<h3>Exercise 1 - STEP 11 (save an image)<a href="genemania_web.html#exercise-1---step-11-save-an-image" class="anchor-section" aria-label="Anchor link to header"></a></h3>
<p><img src="Module6/genemania/images/GM10.png" alt="start" width="60%" /></p>
<p><img src="Module6/genemania/images/GM35_2.png" alt="start" width="60%" /></p>
<p><strong>Notes</strong> about biological interpretation of the results:</p>
<p><strong>A paper describing the interaction between GRN and SORT1 and demonstrates how finding related genes could be relevant for elaborating therapy:</strong></p>
<p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929086/">Targeted manipulation of the sortilin–progranulin axis rescues progranulin haploinsufficiency. Lee et al. Hum Mol Genet. 2014 March 15; 23(6): 1467–1478. PMCID:PMC3929086</a><br>
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</div>
<div id="exercise-3---step-5" class="section level3 hasAnchor">
<h3>Exercise 3 - STEP 5<a href="genemania_web.html#exercise-3---step-5" class="anchor-section" aria-label="Anchor link to header"></a></h3>
<p><img src="Module6/genemania/images/GM31.png" alt="start" width="60%" /></p>
<p><img src="Module6/genemania/images/GM31_v2.png" alt="start" width="60%" /></p>
</div>
<div id="exercise-3---steps-6" class="section level3 hasAnchor">
<h3>Exercise 3 - STEPS 6<a href="genemania_web.html#exercise-3---steps-6" class="anchor-section" aria-label="Anchor link to header"></a></h3>
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</div>
<div id="exercise-3---step-8" class="section level3 hasAnchor">
<h3>Exercise 3 - STEP 8<a href="genemania_web.html#exercise-3---step-8" class="anchor-section" aria-label="Anchor link to header"></a></h3>
<p><img src="Module6/genemania/images/GM35.png" alt="start" width="60%" /></p>
<p><img src="Module6/genemania/images/GM35_2.png" alt="start" width="60%" /></p>
<p><img src="Module6/genemania/images/GM36.png" alt="start" width="60%" /></p>
</div>
<div id="exercise-3---step-9" class="section level3 hasAnchor">
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