In this repository we provide the code for the inference of Hidden Extended Suppes-Bayes Causal Networks (H-ESBCNs) in the directory named "HESBCN" and the scripts to replicate the PMCE analysis as presented in the paper (directory named "Utilities").
For the theoretical and methodological details, please refer to: Fabrizio Angaroni, Kevin Chen, Chiara Damiani, Giulio Caravagna, Alex Graudenzi, Daniele Ramazotti, PMCE: efficient inference of expressive models of cancer evolution with high prognostic power, Bioinformatics, 2021;, btab717, https://doi.org/10.1093/bioinformatics/btab717
Please feel free to contact us if you have problems running our tool at [email protected] and [email protected].