diff --git a/src/plugins/intel_gpu/include/intel_gpu/runtime/layout.hpp b/src/plugins/intel_gpu/include/intel_gpu/runtime/layout.hpp
index 82cf01ab9522b1..62e4c08a90f004 100644
--- a/src/plugins/intel_gpu/include/intel_gpu/runtime/layout.hpp
+++ b/src/plugins/intel_gpu/include/intel_gpu/runtime/layout.hpp
@@ -183,7 +183,7 @@ struct padding {
     }
 
     friend bool operator<(const padding& lhs, const padding& rhs) {
-        OPENVINO_ASSERT(!lhs.is_dynamic() && !rhs.is_dynamic(), "[GPU] padding compare is called for dynamic shape");
+        // Compare only actual padding size not _dynamic_dims_mask
         if (lhs._lower_size < rhs._lower_size) return true;
         else if (lhs._lower_size > rhs._lower_size) return false;
         if (lhs._upper_size < rhs._upper_size) return true;
diff --git a/src/plugins/intel_gpu/src/runtime/memory_pool.cpp b/src/plugins/intel_gpu/src/runtime/memory_pool.cpp
index 9dee7c4487002e..1d34cfcde18a63 100644
--- a/src/plugins/intel_gpu/src/runtime/memory_pool.cpp
+++ b/src/plugins/intel_gpu/src/runtime/memory_pool.cpp
@@ -306,7 +306,7 @@ memory::ptr memory_pool::get_memory(const layout& layout,
     }
     if (do_reuse) {
         // reusable within the same network
-        if (!layout.format.is_image() && layout.data_padding == padding{{0, 0, 0, 0}, 0}) {
+        if (!layout.format.is_image() && !layout.data_padding) {
             // non-padded buffers
             return get_from_non_padded_pool(layout, prim_id, unique_id, network_id, restrictions, type, reset, is_dynamic);
         } else if (!layout.format.is_image()) {