diff --git a/.yarn/versions/56678543.yml b/.yarn/versions/56678543.yml
new file mode 100644
index 000000000000..2d6a48f178d8
--- /dev/null
+++ b/.yarn/versions/56678543.yml
@@ -0,0 +1,34 @@
+releases:
+  "@yarnpkg/cli": patch
+  "@yarnpkg/core": patch
+
+declined:
+  - "@yarnpkg/plugin-compat"
+  - "@yarnpkg/plugin-constraints"
+  - "@yarnpkg/plugin-dlx"
+  - "@yarnpkg/plugin-essentials"
+  - "@yarnpkg/plugin-exec"
+  - "@yarnpkg/plugin-file"
+  - "@yarnpkg/plugin-git"
+  - "@yarnpkg/plugin-github"
+  - "@yarnpkg/plugin-http"
+  - "@yarnpkg/plugin-init"
+  - "@yarnpkg/plugin-interactive-tools"
+  - "@yarnpkg/plugin-link"
+  - "@yarnpkg/plugin-nm"
+  - "@yarnpkg/plugin-npm"
+  - "@yarnpkg/plugin-npm-cli"
+  - "@yarnpkg/plugin-pack"
+  - "@yarnpkg/plugin-patch"
+  - "@yarnpkg/plugin-pnp"
+  - "@yarnpkg/plugin-pnpm"
+  - "@yarnpkg/plugin-stage"
+  - "@yarnpkg/plugin-typescript"
+  - "@yarnpkg/plugin-version"
+  - "@yarnpkg/plugin-workspace-tools"
+  - "@yarnpkg/builder"
+  - "@yarnpkg/doctor"
+  - "@yarnpkg/extensions"
+  - "@yarnpkg/nm"
+  - "@yarnpkg/pnpify"
+  - "@yarnpkg/sdks"
diff --git a/packages/acceptance-tests/pkg-tests-core/sources/utils/makeTemporaryEnv.ts b/packages/acceptance-tests/pkg-tests-core/sources/utils/makeTemporaryEnv.ts
index 971c4b5de7d7..730bfe2fa2b0 100644
--- a/packages/acceptance-tests/pkg-tests-core/sources/utils/makeTemporaryEnv.ts
+++ b/packages/acceptance-tests/pkg-tests-core/sources/utils/makeTemporaryEnv.ts
@@ -58,6 +58,8 @@ const mte = generatePkgDriver({
         [`YARN_ENABLE_GLOBAL_CACHE`]: `false`,
         // Older versions of Windows need this set to not have node throw an error
         [`NODE_SKIP_PLATFORM_CHECK`]: `1`,
+        // We don't want the PnP runtime to be accidentally injected
+        [`NODE_OPTIONS`]: ``,
         ...rcEnv,
         ...env,
       },
diff --git a/packages/acceptance-tests/pkg-tests-specs/sources/commands/constraints.test.ts b/packages/acceptance-tests/pkg-tests-specs/sources/commands/constraints.test.ts
index 5fe8d7692f40..70438674d170 100644
--- a/packages/acceptance-tests/pkg-tests-specs/sources/commands/constraints.test.ts
+++ b/packages/acceptance-tests/pkg-tests-specs/sources/commands/constraints.test.ts
@@ -107,6 +107,23 @@ describe(`Commands`, () => {
       await expect(run(`constraints`)).rejects.toThrow(/This should fail/);
     }));
 
+    it(`should allow requiring dependencies from the yarn.config.cjs file`, makeTemporaryEnv({
+      dependencies: {
+        [`no-deps`]: `1.0.0`,
+      },
+    }, async ({path, run, source}) => {
+      await run(`install`);
+
+      await writeFile(ppath.join(path, `yarn.config.cjs`), `
+        require('no-deps');
+
+        exports.constraints = ({Yarn}) => {
+        };
+      `);
+
+      await run(`constraints`);
+    }));
+
     it(`shouldn't report errors when comparing identical objects`, makeTemporaryEnv({
       foo: {
         ok: true,
diff --git a/packages/yarnpkg-core/sources/Project.ts b/packages/yarnpkg-core/sources/Project.ts
index 57ba94dd4288..a2201624c2c8 100644
--- a/packages/yarnpkg-core/sources/Project.ts
+++ b/packages/yarnpkg-core/sources/Project.ts
@@ -711,6 +711,14 @@ export class Project {
   }
 
   async loadUserConfig() {
+    // TODO: We're injecting the .pnp.cjs in the environment, so that it's
+    // able to required the project dependencies. It's not ideal to hardcode
+    // this logic here, but I'm not quite sure yet what would be a better place.
+    //
+    const pnpPath = ppath.join(this.cwd, `.pnp.cjs`);
+    if (await xfs.existsPromise(pnpPath))
+      miscUtils.dynamicRequire(pnpPath).setup();
+
     const configPath = ppath.join(this.cwd, `yarn.config.cjs`);
     if (!await xfs.existsPromise(configPath))
       return null;