diff --git a/src/cloud-api-adaptor/test/e2e/libvirt_test.go b/src/cloud-api-adaptor/test/e2e/libvirt_test.go
index d4b64d217..0f08ec288 100644
--- a/src/cloud-api-adaptor/test/e2e/libvirt_test.go
+++ b/src/cloud-api-adaptor/test/e2e/libvirt_test.go
@@ -31,6 +31,9 @@ func TestLibvirtCreatePodWithSecret(t *testing.T) {
 
 func TestLibvirtCreatePeerPodContainerWithExternalIPAccess(t *testing.T) {
 	SkipTestOnCI(t)
+	if isTestOnCrio() {
+		t.Skip("Fails with CRI-O (confidential-containers/cloud-api-adaptor#2100)")
+	}
 	assert := LibvirtAssert{}
 	DoTestCreatePeerPodContainerWithExternalIPAccess(t, testEnv, assert)
 
@@ -114,6 +117,9 @@ func TestLibvirtDeletePod(t *testing.T) {
 func TestLibvirtPodToServiceCommunication(t *testing.T) {
 	// This test is causing issues on CI with instability, so skip until we can resolve this.
 	SkipTestOnCI(t)
+	if isTestOnCrio() {
+		t.Skip("Fails with CRI-O (confidential-containers/cloud-api-adaptor#2100)")
+	}
 	assert := LibvirtAssert{}
 	DoTestPodToServiceCommunication(t, testEnv, assert)
 }
@@ -121,6 +127,9 @@ func TestLibvirtPodToServiceCommunication(t *testing.T) {
 func TestLibvirtPodsMTLSCommunication(t *testing.T) {
 	// This test is causing issues on CI with instability, so skip until we can resolve this.
 	SkipTestOnCI(t)
+	if isTestOnCrio() {
+		t.Skip("Fails with CRI-O (confidential-containers/cloud-api-adaptor#2100)")
+	}
 	assert := LibvirtAssert{}
 	DoTestPodsMTLSCommunication(t, testEnv, assert)
 }
@@ -130,6 +139,10 @@ func TestLibvirtImageDecryption(t *testing.T) {
 		t.Skip("Skipping kbs related test as kbs is not deployed")
 	}
 
+	if isTestOnCrio() {
+		t.Skip("Image decryption not supported with CRI-O")
+	}
+
 	assert := LibvirtAssert{}
 	DoTestImageDecryption(t, testEnv, assert, keyBrokerService)
 }