ontology.graphml

<?xml version='1.0' encoding='utf-8'?>
<graphml xmlns="http://graphml.graphdrawing.org/xmlns" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://graphml.graphdrawing.org/xmlns http://graphml.graphdrawing.org/xmlns/1.0/graphml.xsd">
  <key id="virtual" for="node" attr.name="virtual" attr.type="boolean" />
  <key id="inherit_properties" for="node" attr.name="inherit_properties" attr.type="boolean" />
  <key id="is_a" for="node" attr.name="is_a" attr.type="string" />
  <key id="user_extension" for="node" attr.name="user_extension" attr.type="boolean" />
  <key id="properties" for="node" attr.name="properties" attr.type="string" />
  <key id="exclude_properties" for="node" attr.name="exclude_properties" attr.type="string" />
  <key id="input_label" for="node" attr.name="input_label" attr.type="string" />
  <key id="label_as_edge" for="node" attr.name="label_as_edge" attr.type="string" />
  <key id="preferred_id" for="node" attr.name="preferred_id" attr.type="string" />
  <key id="label_in_input" for="node" attr.name="label_in_input" attr.type="string" />
  <key id="target" for="node" attr.name="target" attr.type="string" />
  <key id="source" for="node" attr.name="source" attr.type="string" />
  <key id="represented_as" for="node" attr.name="represented_as" attr.type="string" />
  <key id="label" for="node" attr.name="label" attr.type="string" />
  <graph edgedefault="directed">
    <node id="Entity">
      <data key="label">entity</data>
    </node>
    <node id="Association">
      <data key="label">association</data>
    </node>
    <node id="BehaviorToBehavioralFeatureAssociation">
      <data key="label">behavior to behavioral feature association</data>
    </node>
    <node id="EntityToPhenotypicFeatureAssociationMixin">
      <data key="label">entity to phenotypic feature association mixin</data>
    </node>
    <node id="EntityToFeatureOrDiseaseQualifiersMixin">
      <data key="label">entity to feature or disease qualifiers mixin</data>
    </node>
    <node id="FrequencyQualifierMixin">
      <data key="label">frequency qualifier mixin</data>
    </node>
    <node id="FrequencyQuantifier">
      <data key="label">frequency quantifier</data>
    </node>
    <node id="RelationshipQuantifier">
      <data key="label">relationship quantifier</data>
    </node>
    <node id="CaseToPhenotypicFeatureAssociation">
      <data key="label">case to phenotypic feature association</data>
    </node>
    <node id="CaseToEntityAssociationMixin">
      <data key="label">case to entity association mixin</data>
    </node>
    <node id="ChemicalAffectsGeneAssociation">
      <data key="label">chemical affects gene association</data>
    </node>
    <node id="ChemicalEntityAssessesNamedThingAssociation">
      <data key="label">chemical entity assesses named thing association</data>
    </node>
    <node id="ChemicalEntityOrGeneOrGeneProductRegulatesGeneAssociation">
      <data key="label">chemical entity or gene or gene product regulates gene association</data>
    </node>
    <node id="ChemicalGeneInteractionAssociation">
      <data key="label">chemical gene interaction association</data>
    </node>
    <node id="ChemicalToEntityAssociationMixin">
      <data key="label">chemical to entity association mixin</data>
    </node>
    <node id="ChemicalEntityToEntityAssociationMixin">
      <data key="label">chemical entity to entity association mixin</data>
    </node>
    <node id="ChemicalToDiseaseOrPhenotypicFeatureAssociation">
      <data key="label">chemical to disease or phenotypic feature association</data>
    </node>
    <node id="EntityToDiseaseOrPhenotypicFeatureAssociationMixin">
      <data key="label">entity to disease or phenotypic feature association mixin</data>
    </node>
    <node id="ChemicalToPathwayAssociation">
      <data key="label">chemical to pathway association</data>
    </node>
    <node id="ContributorAssociation">
      <data key="label">contributor association</data>
    </node>
    <node id="DiseaseOrPhenotypicFeatureToGeneticInheritanceAssociation">
      <data key="label">disease or phenotypic feature to genetic inheritance association</data>
    </node>
    <node id="DiseaseOrPhenotypicFeatureToEntityAssociationMixin">
      <data key="label">disease or phenotypic feature to entity association mixin</data>
    </node>
    <node id="DiseaseOrPhenotypicFeatureToLocationAssociation">
      <data key="label">disease or phenotypic feature to location association</data>
    </node>
    <node id="DiseaseToExposureEventAssociation">
      <data key="label">disease to exposure event association</data>
    </node>
    <node id="DiseaseToEntityAssociationMixin">
      <data key="label">disease to entity association mixin</data>
    </node>
    <node id="EntityToExposureEventAssociationMixin">
      <data key="label">entity to exposure event association mixin</data>
    </node>
    <node id="DiseaseToPhenotypicFeatureAssociation">
      <data key="label">disease to phenotypic feature association</data>
    </node>
    <node id="DrugToGeneAssociation">
      <data key="label">drug to gene association</data>
    </node>
    <node id="DrugToEntityAssociationMixin">
      <data key="label">drug to entity association mixin</data>
    </node>
    <node id="EntityToDiseaseAssociation">
      <data key="label">entity to disease association</data>
    </node>
    <node id="EntityToPhenotypicFeatureAssociation">
      <data key="label">entity to phenotypic feature association</data>
    </node>
    <node id="ExposureEventToOutcomeAssociation">
      <data key="label">exposure event to outcome association</data>
    </node>
    <node id="EntityToOutcomeAssociationMixin">
      <data key="label">entity to outcome association mixin</data>
    </node>
    <node id="ExposureEventToPhenotypicFeatureAssociation">
      <data key="label">exposure event to phenotypic feature association</data>
    </node>
    <node id="GeneToExpressionSiteAssociation">
      <data key="label">gene to expression site association</data>
    </node>
    <node id="GeneToGeneFamilyAssociation">
      <data key="label">gene to gene family association</data>
    </node>
    <node id="GeneToPathwayAssociation">
      <data key="label">gene to pathway association</data>
    </node>
    <node id="GeneToEntityAssociationMixin">
      <data key="label">gene to entity association mixin</data>
    </node>
    <node id="GeneToPhenotypicFeatureAssociation">
      <data key="label">gene to phenotypic feature association</data>
    </node>
    <node id="GenotypeToGeneAssociation">
      <data key="label">genotype to gene association</data>
    </node>
    <node id="GenotypeToGenotypePartAssociation">
      <data key="label">genotype to genotype part association</data>
    </node>
    <node id="GenotypeToPhenotypicFeatureAssociation">
      <data key="label">genotype to phenotypic feature association</data>
    </node>
    <node id="GenotypeToEntityAssociationMixin">
      <data key="label">genotype to entity association mixin</data>
    </node>
    <node id="GenotypeToVariantAssociation">
      <data key="label">genotype to variant association</data>
    </node>
    <node id="InformationContentEntityToNamedThingAssociation">
      <data key="label">information content entity to named thing association</data>
    </node>
    <node id="MaterialSampleDerivationAssociation">
      <data key="label">material sample derivation association</data>
    </node>
    <node id="MaterialSampleToDiseaseOrPhenotypicFeatureAssociation">
      <data key="label">material sample to disease or phenotypic feature association</data>
    </node>
    <node id="MaterialSampleToEntityAssociationMixin">
      <data key="label">material sample to entity association mixin</data>
    </node>
    <node id="MolecularActivityToChemicalEntityAssociation">
      <data key="label">molecular activity to chemical entity association</data>
    </node>
    <node id="MolecularActivityToMolecularActivityAssociation">
      <data key="label">molecular activity to molecular activity association</data>
    </node>
    <node id="MolecularActivityToPathwayAssociation">
      <data key="label">molecular activity to pathway association</data>
    </node>
    <node id="NamedThingAssociatedWithLikelihoodOfNamedThingAssociation">
      <data key="label">named thing associated with likelihood of named thing association</data>
    </node>
    <node id="OrganismTaxonToEnvironmentAssociation">
      <data key="label">organism taxon to environment association</data>
    </node>
    <node id="OrganismTaxonToEntityAssociation">
      <data key="label">organism taxon to entity association</data>
    </node>
    <node id="OrganismToOrganismAssociation">
      <data key="label">organism to organism association</data>
    </node>
    <node id="OrganismalEntityAsAModelOfDiseaseAssociation">
      <data key="label">organismal entity as a model of disease association</data>
    </node>
    <node id="EntityToDiseaseAssociationMixin">
      <data key="label">entity to disease association mixin</data>
    </node>
    <node id="ModelToDiseaseAssociationMixin">
      <data key="label">model to disease association mixin</data>
    </node>
    <node id="PopulationToPopulationAssociation">
      <data key="label">population to population association</data>
    </node>
    <node id="SequenceVariantModulatesTreatmentAssociation">
      <data key="label">sequence variant modulates treatment association</data>
    </node>
    <node id="TaxonToTaxonAssociation">
      <data key="label">taxon to taxon association</data>
    </node>
    <node id="VariantToPhenotypicFeatureAssociation">
      <data key="label">variant to phenotypic feature association</data>
    </node>
    <node id="VariantToEntityAssociationMixin">
      <data key="label">variant to entity association mixin</data>
    </node>
    <node id="VariantToPopulationAssociation">
      <data key="label">variant to population association</data>
    </node>
    <node id="CellLineToDiseaseOrPhenotypicFeatureAssociation">
      <data key="label">cell line to disease or phenotypic feature association</data>
    </node>
    <node id="CellLineAsAModelOfDiseaseAssociation">
      <data key="label">cell line as a model of disease association</data>
    </node>
    <node id="CellLineToEntityAssociationMixin">
      <data key="label">cell line to entity association mixin</data>
    </node>
    <node id="ChemicalOrDrugOrTreatmentToDiseaseOrPhenotypicFeatureAssociation">
      <data key="label">chemical or drug or treatment to disease or phenotypic feature association</data>
    </node>
    <node id="ChemicalOrDrugOrTreatmentSideEffectDiseaseOrPhenotypicFeatureAssociation">
      <data key="label">chemical or drug or treatment side effect disease or phenotypic feature association</data>
    </node>
    <node id="GenotypeToDiseaseAssociation">
      <data key="label">genotype to disease association</data>
    </node>
    <node id="GenotypeAsAModelOfDiseaseAssociation">
      <data key="label">genotype as a model of disease association</data>
    </node>
    <node id="SequenceAssociation">
      <data key="label">sequence association</data>
    </node>
    <node id="GenomicSequenceLocalization">
      <data key="label">genomic sequence localization</data>
    </node>
    <node id="VariantToDiseaseAssociation">
      <data key="label">variant to disease association</data>
    </node>
    <node id="VariantAsAModelOfDiseaseAssociation">
      <data key="label">variant as a model of disease association</data>
    </node>
    <node id="VariantToGeneAssociation">
      <data key="label">variant to gene association</data>
      <data key="represented_as">edge</data>
      <data key="source">['known.sequence variant', 'somatic.sequence variant']</data>
      <data key="target">gene</data>
      <data key="label_in_input">['VARIANT_FOUND_IN_GENE_Known_variant_Gene', 'VARIANT_FOUND_IN_GENE_Somatic_mutation_Gene']</data>
      <data key="preferred_id">id</data>
    </node>
    <node id="VariantToGeneExpressionAssociation">
      <data key="label">variant to gene expression association</data>
    </node>
    <node id="GeneExpressionMixin">
      <data key="label">gene expression mixin</data>
    </node>
    <node id="AnatomicalEntityToAnatomicalEntityAssociation">
      <data key="label">anatomical entity to anatomical entity association</data>
    </node>
    <node id="AnatomicalEntityToAnatomicalEntityOntogenicAssociation">
      <data key="label">anatomical entity to anatomical entity ontogenic association</data>
    </node>
    <node id="AnatomicalEntityToAnatomicalEntityPartOfAssociation">
      <data key="label">anatomical entity to anatomical entity part of association</data>
    </node>
    <node id="ChemicalToChemicalAssociation">
      <data key="label">chemical to chemical association</data>
    </node>
    <node id="ChemicalToChemicalDerivationAssociation">
      <data key="label">chemical to chemical derivation association</data>
    </node>
    <node id="ReactionToParticipantAssociation">
      <data key="label">reaction to participant association</data>
    </node>
    <node id="ReactionToCatalystAssociation">
      <data key="label">reaction to catalyst association</data>
    </node>
    <node id="OrganismTaxonToOrganismTaxonAssociation">
      <data key="label">organism taxon to organism taxon association</data>
    </node>
    <node id="OrganismTaxonToOrganismTaxonInteraction">
      <data key="label">organism taxon to organism taxon interaction</data>
    </node>
    <node id="OrganismTaxonToOrganismTaxonSpecialization">
      <data key="label">organism taxon to organism taxon specialization</data>
    </node>
    <node id="GeneToDiseaseAssociation">
      <data key="label">gene to disease association</data>
      <data key="represented_as">edge</data>
      <data key="label_as_edge">PERTURBED_IN_DISEASE</data>
      <data key="input_label">['protein_disease', 'gene_disease']</data>
      <data key="exclude_properties">accession</data>
      <data key="preferred_id">id</data>
    </node>
    <node id="DruggableGeneToDiseaseAssociation">
      <data key="label">druggable gene to disease association</data>
    </node>
    <node id="GeneAsAModelOfDiseaseAssociation">
      <data key="label">gene as a model of disease association</data>
    </node>
    <node id="GeneHasVariantThatContributesToDiseaseAssociation">
      <data key="label">gene has variant that contributes to disease association</data>
    </node>
    <node id="GeneToGeneAssociation">
      <data key="label">gene to gene association</data>
      <data key="represented_as">edge</data>
      <data key="label_in_input">gene_gene</data>
      <data key="properties">{'directional': 'bool', 'curated': 'bool', 'score': 'float'}</data>
      <data key="preferred_id">id</data>
    </node>
    <node id="GeneToGeneCoexpressionAssociation">
      <data key="label">gene to gene coexpression association</data>
    </node>
    <node id="GeneToGeneHomologyAssociation">
      <data key="label">gene to gene homology association</data>
    </node>
    <node id="PairwiseGeneToGeneInteraction">
      <data key="label">pairwise gene to gene interaction</data>
    </node>
    <node id="PairwiseMolecularInteraction">
      <data key="label">pairwise molecular interaction</data>
    </node>
    <node id="SequenceFeatureRelationship">
      <data key="label">sequence feature relationship</data>
    </node>
    <node id="ExonToTranscriptRelationship">
      <data key="label">exon to transcript relationship</data>
    </node>
    <node id="GeneToGeneProductRelationship">
      <data key="label">gene to gene product relationship</data>
    </node>
    <node id="TranscriptToGeneRelationship">
      <data key="label">transcript to gene relationship</data>
    </node>
    <node id="FunctionalAssociation">
      <data key="label">functional association</data>
    </node>
    <node id="GeneToGoTermAssociation">
      <data key="label">gene to go term association</data>
    </node>
    <node id="MacromolecularMachineToBiologicalProcessAssociation">
      <data key="label">macromolecular machine to biological process association</data>
    </node>
    <node id="MacromolecularMachineToEntityAssociationMixin">
      <data key="label">macromolecular machine to entity association mixin</data>
    </node>
    <node id="MacromolecularMachineToCellularComponentAssociation">
      <data key="label">macromolecular machine to cellular component association</data>
    </node>
    <node id="MacromolecularMachineToMolecularActivityAssociation">
      <data key="label">macromolecular machine to molecular activity association</data>
    </node>
    <node id="NamedThing">
      <data key="label">named thing</data>
    </node>
    <node id="Activity">
      <data key="label">activity</data>
    </node>
    <node id="ActivityAndBehavior">
      <data key="label">activity and behavior</data>
    </node>
    <node id="Occurrent">
      <data key="label">occurrent</data>
    </node>
    <node id="PhysicalEssenceOrOccurrent">
      <data key="label">physical essence or occurrent</data>
    </node>
    <node id="Event">
      <data key="label">event</data>
    </node>
    <node id="Phenomenon">
      <data key="label">phenomenon</data>
    </node>
    <node id="AdministrativeEntity">
      <data key="label">administrative entity</data>
    </node>
    <node id="Agent">
      <data key="label">agent</data>
    </node>
    <node id="Treatment">
      <data key="label">treatment</data>
    </node>
    <node id="ChemicalOrDrugOrTreatment">
      <data key="label">chemical or drug or treatment</data>
    </node>
    <node id="ExposureEvent">
      <data key="label">exposure event</data>
    </node>
    <node id="OntologyClass">
      <data key="label">ontology class</data>
    </node>
    <node id="ClinicalEntity">
      <data key="label">clinical entity</data>
    </node>
    <node id="ClinicalTrial">
      <data key="label">clinical trial</data>
    </node>
    <node id="ClinicalIntervention">
      <data key="label">clinical intervention</data>
    </node>
    <node id="Hospitalization">
      <data key="label">hospitalization</data>
    </node>
    <node id="Device">
      <data key="label">device</data>
    </node>
    <node id="Procedure">
      <data key="label">procedure</data>
    </node>
    <node id="PlanetaryEntity">
      <data key="label">planetary entity</data>
    </node>
    <node id="EnvironmentalFeature">
      <data key="label">environmental feature</data>
    </node>
    <node id="EnvironmentalProcess">
      <data key="label">environmental process</data>
    </node>
    <node id="GeographicLocation">
      <data key="label">geographic location</data>
    </node>
    <node id="GeographicLocationAtTime">
      <data key="label">geographic location at time</data>
    </node>
    <node id="PhysicalEntity">
      <data key="label">physical entity</data>
    </node>
    <node id="MaterialSample">
      <data key="label">material sample</data>
    </node>
    <node id="SubjectOfInvestigation">
      <data key="label">subject of investigation</data>
    </node>
    <node id="PhysicalEssence">
      <data key="label">physical essence</data>
    </node>
    <node id="OrganismTaxon">
      <data key="label">organism taxon</data>
    </node>
    <node id="InformationContentEntity">
      <data key="label">information content entity</data>
    </node>
    <node id="CommonDataElement">
      <data key="label">common data element</data>
    </node>
    <node id="Study">
      <data key="label">study</data>
    </node>
    <node id="StudyVariable">
      <data key="label">study variable</data>
    </node>
    <node id="ConfidenceLevel">
      <data key="label">confidence level</data>
    </node>
    <node id="EvidenceType">
      <data key="label">evidence type</data>
    </node>
    <node id="DatasetDistribution">
      <data key="label">dataset distribution</data>
    </node>
    <node id="DatasetSummary">
      <data key="label">dataset summary</data>
    </node>
    <node id="DatasetVersion">
      <data key="label">dataset version</data>
    </node>
    <node id="Dataset">
      <data key="label">dataset</data>
    </node>
    <node id="StudyResult">
      <data key="label">study result</data>
    </node>
    <node id="ChiSquaredAnalysisResult">
      <data key="label">chi squared analysis result</data>
    </node>
    <node id="ConceptCountAnalysisResult">
      <data key="label">concept count analysis result</data>
    </node>
    <node id="ObservedExpectedFrequencyAnalysisResult">
      <data key="label">observed expected frequency analysis result</data>
    </node>
    <node id="RelativeFrequencyAnalysisResult">
      <data key="label">relative frequency analysis result</data>
    </node>
    <node id="TextMiningResult">
      <data key="label">text mining result</data>
    </node>
    <node id="InformationResource">
      <data key="label">information resource</data>
    </node>
    <node id="Publication">
      <data key="label">publication</data>
    </node>
    <node id="Article">
      <data key="label">article</data>
    </node>
    <node id="Book">
      <data key="label">book</data>
    </node>
    <node id="Serial">
      <data key="label">serial</data>
    </node>
    <node id="BookChapter">
      <data key="label">book chapter</data>
    </node>
    <node id="BiologicalEntity">
      <data key="label">biological entity</data>
    </node>
    <node id="Genome">
      <data key="label">genome</data>
    </node>
    <node id="GenomicEntity">
      <data key="label">genomic entity</data>
    </node>
    <node id="Haplotype">
      <data key="label">haplotype</data>
    </node>
    <node id="MacromolecularComplex">
      <data key="label">complex</data>
    </node>
    <node id="MacromolecularMachineMixin">
      <data key="label">macromolecular machine mixin</data>
    </node>
    <node id="NucleicAcidSequenceMotif">
      <data key="label">nucleic acid sequence motif</data>
    </node>
    <node id="NucleosomeModification">
      <data key="label">nucleosome modification</data>
    </node>
    <node id="EpigenomicEntity">
      <data key="label">epigenomic entity</data>
    </node>
    <node id="GeneProductIsoformMixin">
      <data key="label">gene product isoform mixin</data>
    </node>
    <node id="GeneProductMixin">
      <data key="label">gene product mixin</data>
    </node>
    <node id="GeneOrGeneProduct">
      <data key="label">gene or gene product</data>
    </node>
    <node id="PosttranslationalModification">
      <data key="label">posttranslational modification</data>
    </node>
    <node id="ProteinDomain">
      <data key="label">protein domain</data>
    </node>
    <node id="ChemicalEntityOrGeneOrGeneProduct">
      <data key="label">chemical entity or gene or gene product</data>
    </node>
    <node id="GeneGroupingMixin">
      <data key="label">gene grouping mixin</data>
    </node>
    <node id="ProteinFamily">
      <data key="label">protein family</data>
    </node>
    <node id="ReagentTargetedGene">
      <data key="label">reagent targeted gene</data>
    </node>
    <node id="GeneFamily">
      <data key="label">gene family</data>
    </node>
    <node id="Polypeptide">
      <data key="label">polypeptide</data>
    </node>
    <node id="Protein">
      <data key="label">protein</data>
      <data key="represented_as">node</data>
      <data key="preferred_id">uniprot</data>
      <data key="input_label">protein</data>
      <data key="properties">{'name': 'str', 'score': 'float', 'taxon': 'int', 'genes': 'str[]'}</data>
    </node>
    <node id="ProteinIsoform">
      <data key="label">protein isoform</data>
    </node>
    <node id="ChemicalEntityOrProteinOrPolypeptide">
      <data key="label">chemical entity or protein or polypeptide</data>
    </node>
    <node id="GeneticInheritance">
      <data key="label">genetic inheritance</data>
    </node>
    <node id="Genotype">
      <data key="label">genotype</data>
    </node>
    <node id="OrganismalEntity">
      <data key="label">organismal entity</data>
    </node>
    <node id="CellularOrganism">
      <data key="label">cellular organism</data>
    </node>
    <node id="Virus">
      <data key="label">virus</data>
    </node>
    <node id="CellLine">
      <data key="label">cell line</data>
    </node>
    <node id="IndividualOrganism">
      <data key="label">individual organism</data>
    </node>
    <node id="Case">
      <data key="label">case</data>
    </node>
    <node id="LifeStage">
      <data key="label">life stage</data>
    </node>
    <node id="PopulationOfIndividualOrganisms">
      <data key="label">population of individual organisms</data>
    </node>
    <node id="StudyPopulation">
      <data key="label">study population</data>
    </node>
    <node id="Cohort">
      <data key="label">cohort</data>
    </node>
    <node id="AnatomicalEntity">
      <data key="label">anatomical entity</data>
    </node>
    <node id="Cell">
      <data key="label">cell</data>
    </node>
    <node id="GrossAnatomicalStructure">
      <data key="label">gross anatomical structure</data>
    </node>
    <node id="PathologicalAnatomicalStructure">
      <data key="label">pathological anatomical structure</data>
    </node>
    <node id="PathologicalEntityMixin">
      <data key="label">pathological entity mixin</data>
    </node>
    <node id="CellularComponent">
      <data key="label">cellular component</data>
    </node>
    <node id="BiologicalProcessOrActivity">
      <data key="label">biological process or activity</data>
    </node>
    <node id="MolecularActivity">
      <data key="label">molecular activity</data>
    </node>
    <node id="BiologicalProcess">
      <data key="label">biological process</data>
    </node>
    <node id="PathologicalProcess">
      <data key="label">pathological process</data>
    </node>
    <node id="PhysiologicalProcess">
      <data key="label">physiological process</data>
    </node>
    <node id="Behavior">
      <data key="label">behavior</data>
    </node>
    <node id="Pathway">
      <data key="label">pathway</data>
      <data key="represented_as">node</data>
      <data key="preferred_id">['reactome', 'wikipathways']</data>
      <data key="input_label">['reactome', 'wikipathways']</data>
    </node>
    <node id="SO_0001060">
      <data key="label">sequence variant</data>
      <data key="represented_as">node</data>
      <data key="preferred_id">['clinically relevant', 'known', 'somatic']</data>
      <data key="label_in_input">['Clinically_relevant_variant', 'Known_variant', 'Somatic_mutation']</data>
      <data key="properties">{'source': 'str', 'original_source': 'str', 'effect': 'str', 'biotype': 'str'}</data>
    </node>
    <node id="Snv">
      <data key="label">snv</data>
    </node>
    <node id="Gene">
      <data key="label">gene</data>
      <data key="represented_as">node</data>
      <data key="preferred_id">hgnc</data>
      <data key="label_in_input">['hgnc', 'ensg']</data>
      <data key="exclude_properties">accession</data>
    </node>
    <node id="DiseaseOrPhenotypicFeature">
      <data key="label">disease or phenotypic feature</data>
    </node>
    <node id="PhenotypicFeature">
      <data key="label">phenotypic feature</data>
    </node>
    <node id="ClinicalFinding">
      <data key="label">clinical finding</data>
    </node>
    <node id="BehavioralFeature">
      <data key="label">behavioral feature</data>
    </node>
    <node id="MONDO_0000001">
      <data key="label">disease</data>
      <data key="represented_as">node</data>
      <data key="preferred_id">doid</data>
      <data key="label_in_input">Disease</data>
    </node>
    <node id="ThingWithTaxon">
      <data key="label">thing with taxon</data>
    </node>
    <node id="Attribute">
      <data key="label">attribute</data>
    </node>
    <node id="BehavioralExposure">
      <data key="label">behavioral exposure</data>
    </node>
    <node id="BioticExposure">
      <data key="label">biotic exposure</data>
    </node>
    <node id="ComplexChemicalExposure">
      <data key="label">complex chemical exposure</data>
    </node>
    <node id="DiseaseOrPhenotypicFeatureExposure">
      <data key="label">disease or phenotypic feature exposure</data>
    </node>
    <node id="GenomicBackgroundExposure">
      <data key="label">genomic background exposure</data>
    </node>
    <node id="PathologicalAnatomicalExposure">
      <data key="label">pathological anatomical exposure</data>
    </node>
    <node id="PathologicalProcessExposure">
      <data key="label">pathological process exposure</data>
    </node>
    <node id="SocioeconomicExposure">
      <data key="label">socioeconomic exposure</data>
    </node>
    <node id="ChemicalExposure">
      <data key="label">chemical exposure</data>
    </node>
    <node id="DrugExposure">
      <data key="label">drug exposure</data>
    </node>
    <node id="DrugToGeneInteractionExposure">
      <data key="label">drug to gene interaction exposure</data>
    </node>
    <node id="EnvironmentalExposure">
      <data key="label">environmental exposure</data>
    </node>
    <node id="GeographicExposure">
      <data key="label">geographic exposure</data>
    </node>
    <node id="OrganismAttribute">
      <data key="label">organism attribute</data>
    </node>
    <node id="PhenotypicQuality">
      <data key="label">phenotypic quality</data>
    </node>
    <node id="ChemicalRole">
      <data key="label">chemical role</data>
    </node>
    <node id="SocioeconomicAttribute">
      <data key="label">socioeconomic attribute</data>
    </node>
    <node id="Zygosity">
      <data key="label">zygosity</data>
    </node>
    <node id="ClinicalAttribute">
      <data key="label">clinical attribute</data>
    </node>
    <node id="ClinicalMeasurement">
      <data key="label">clinical measurement</data>
    </node>
    <node id="ClinicalCourse">
      <data key="label">clinical course</data>
    </node>
    <node id="Onset">
      <data key="label">onset</data>
    </node>
    <node id="ClinicalModifier">
      <data key="label">clinical modifier</data>
    </node>
    <node id="BiologicalSex">
      <data key="label">biological sex</data>
    </node>
    <node id="GenotypicSex">
      <data key="label">genotypic sex</data>
    </node>
    <node id="PhenotypicSex">
      <data key="label">phenotypic sex</data>
    </node>
    <node id="SeverityValue">
      <data key="label">severity value</data>
    </node>
    <node id="ChemicalEntity">
      <data key="label">chemical entity</data>
    </node>
    <node id="EnvironmentalFoodContaminant">
      <data key="label">environmental food contaminant</data>
    </node>
    <node id="FoodAdditive">
      <data key="label">food additive</data>
    </node>
    <node id="ChemicalMixture">
      <data key="label">chemical mixture</data>
    </node>
    <node id="ComplexMolecularMixture">
      <data key="label">complex molecular mixture</data>
    </node>
    <node id="Food">
      <data key="label">food</data>
    </node>
    <node id="ProcessedMaterial">
      <data key="label">processed material</data>
    </node>
    <node id="MolecularMixture">
      <data key="label">molecular mixture</data>
    </node>
    <node id="Drug">
      <data key="label">drug</data>
    </node>
    <node id="MolecularEntity">
      <data key="label">molecular entity</data>
    </node>
    <node id="SmallMolecule">
      <data key="label">small molecule</data>
    </node>
    <node id="NucleicAcidEntity">
      <data key="label">nucleic acid entity</data>
    </node>
    <node id="CodingSequence">
      <data key="label">coding sequence</data>
    </node>
    <node id="Exon">
      <data key="label">exon</data>
    </node>
    <node id="Transcript">
      <data key="label">transcript</data>
    </node>
    <node id="RNAProduct">
      <data key="label">RNA product</data>
    </node>
    <node id="RNAProductIsoform">
      <data key="label">RNA product isoform</data>
    </node>
    <node id="NoncodingRNAProduct">
      <data key="label">noncoding RNA product</data>
    </node>
    <node id="MicroRNA">
      <data key="label">microRNA</data>
      <data key="represented_as">node</data>
      <data key="preferred_id">mirbase.mature</data>
      <data key="label_in_input">mirna</data>
    </node>
    <node id="SiRNA">
      <data key="label">siRNA</data>
    </node>
    <node id="SO_0001536">
      <data key="label">functional effect variant</data>
    </node>
    <node id="SO_0002218">
      <data key="label">functionally abnormal</data>
    </node>
    <node id="SO_0001773">
      <data key="label">lethal variant</data>
      <data key="represented_as">node</data>
      <data key="label_in_input">lethal</data>
      <data key="preferred_id">id</data>
    </node>
    <node id="SO_0002314">
      <data key="label">altered gene product level</data>
      <data key="represented_as">node</data>
      <data key="label_in_input">agpl</data>
      <data key="preferred_id">id</data>
    </node>
    <node id="SO_0002316">
      <data key="label">decreased gene product level</data>
      <data key="represented_as">node</data>
      <data key="label_in_input">agpl_decreased</data>
      <data key="preferred_id">id</data>
    </node>
    <node id="MONDO_0700096">
      <data key="label">human disease</data>
    </node>
    <node id="MONDO_0002025">
      <data key="label">psychiatric disorder</data>
    </node>
    <node id="MONDO_0024429">
      <data key="label">Alice in Wonderland syndrome</data>
    </node>
    <node id="MONDO_0800105">
      <data key="label">catatonia</data>
    </node>
    <node id="MONDO_0003847">
      <data key="label">hereditary disease</data>
    </node>
    <node id="MONDO_0000429">
      <data key="label">autosomal genetic disease</data>
    </node>
    <node id="MONDO_0006025">
      <data key="label">autosomal recessive disease</data>
    </node>
    <node id="MONDO_0009061">
      <data key="label">cystic fibrosis</data>
    </node>
    <node id="SideEffect">
      <data key="label">side effect</data>
      <data key="user_extension">True</data>
      <data key="is_a">phenotypic feature</data>
      <data key="represented_as">node</data>
      <data key="preferred_id">sider.effect</data>
      <data key="label_in_input">sider</data>
    </node>
    <node id="SnRNASequence">
      <data key="label">snRNA sequence</data>
      <data key="user_extension">True</data>
      <data key="is_a">nucleic acid entity</data>
      <data key="represented_as">node</data>
      <data key="preferred_id">['intact', 'rnacentral']</data>
      <data key="label_in_input">['intact_snrna', 'rnacentral_snrna']</data>
      <data key="properties">{'ac': 'str', 'fullName': 'str', 'shortName': 'str', 'preferredName': 'str'}</data>
      <data key="exclude_properties">sequence</data>
    </node>
    <node id="DNASequence">
      <data key="label">DNA sequence</data>
      <data key="user_extension">True</data>
      <data key="is_a">nucleic acid entity</data>
      <data key="represented_as">node</data>
      <data key="preferred_id">ensembl</data>
      <data key="label_in_input">dna</data>
      <data key="properties">{'ac': 'str', 'fullName': 'str', 'shortName': 'str', 'preferredName': 'str', 'sequence': 'str'}</data>
    </node>
    <node id="DsDNASequence">
      <data key="label">dsDNA sequence</data>
      <data key="user_extension">True</data>
      <data key="is_a">['DNA sequence', 'nucleic acid entity']</data>
      <data key="inherit_properties">True</data>
      <data key="represented_as">node</data>
      <data key="preferred_id">['intact', 'uniparc']</data>
      <data key="label_in_input">['intact_dsdna', 'uniprot_archive_dsdna']</data>
      <data key="properties">{'ac': 'str', 'fullName': 'str', 'shortName': 'str', 'preferredName': 'str', 'sequence': 'str'}</data>
      <data key="exclude_properties">{}</data>
    </node>
    <node id="PostTranslationalInteraction">
      <data key="label">post translational interaction</data>
      <data key="user_extension">True</data>
      <data key="is_a">pairwise molecular interaction</data>
      <data key="represented_as">node</data>
      <data key="label_as_edge">INTERACTS_POST_TRANSLATIONAL</data>
      <data key="label_in_input">post_translational</data>
      <data key="preferred_id">id</data>
    </node>
    <node id="Phosphorylation">
      <data key="label">phosphorylation</data>
      <data key="user_extension">True</data>
      <data key="is_a">post translational interaction</data>
      <data key="represented_as">edge</data>
      <data key="label_in_input">phosphorylation</data>
      <data key="preferred_id">id</data>
    </node>
    <node id="GenotypeToTissueAssociation">
      <data key="label">genotype to tissue association</data>
      <data key="user_extension">True</data>
    </node>
    <node id="MutationToTissueAssociation">
      <data key="label">mutation to tissue association</data>
      <data key="user_extension">True</data>
      <data key="is_a">['genotype to tissue association', 'entity to tissue association', 'association']</data>
      <data key="represented_as">edge</data>
      <data key="label_as_edge">Is_Mutated_In</data>
      <data key="label_in_input">Gene_Is_Mutated_In_Cell_Tissue</data>
      <data key="preferred_id">id</data>
    </node>
    <node id="EntityToTissueAssociation">
      <data key="label">entity to tissue association</data>
      <data key="user_extension">True</data>
    </node>
    <node id="Reactome.pathway">
      <data key="label">reactome.pathway</data>
      <data key="user_extension">True</data>
      <data key="preferred_id">reactome</data>
      <data key="input_label">reactome</data>
      <data key="represented_as">node</data>
      <data key="virtual">True</data>
      <data key="is_a">pathway</data>
    </node>
    <node id="Wikipathways.pathway">
      <data key="label">wikipathways.pathway</data>
      <data key="user_extension">True</data>
      <data key="preferred_id">wikipathways</data>
      <data key="input_label">wikipathways</data>
      <data key="represented_as">node</data>
      <data key="virtual">True</data>
      <data key="is_a">pathway</data>
    </node>
    <node id="ClinicallyRelevant.sequenceVariant">
      <data key="label">clinically relevant.sequence variant</data>
      <data key="user_extension">True</data>
      <data key="preferred_id">clinically relevant</data>
      <data key="input_label">Clinically_relevant_variant</data>
      <data key="represented_as">node</data>
      <data key="virtual">True</data>
      <data key="is_a">sequence variant</data>
      <data key="properties">{'source': 'str', 'original_source': 'str', 'effect': 'str', 'biotype': 'str'}</data>
    </node>
    <node id="Known.sequenceVariant">
      <data key="label">known.sequence variant</data>
      <data key="user_extension">True</data>
      <data key="preferred_id">known</data>
      <data key="input_label">Known_variant</data>
      <data key="represented_as">node</data>
      <data key="virtual">True</data>
      <data key="is_a">sequence variant</data>
      <data key="properties">{'source': 'str', 'original_source': 'str', 'effect': 'str', 'biotype': 'str'}</data>
    </node>
    <node id="Somatic.sequenceVariant">
      <data key="label">somatic.sequence variant</data>
      <data key="user_extension">True</data>
      <data key="preferred_id">somatic</data>
      <data key="input_label">Somatic_mutation</data>
      <data key="represented_as">node</data>
      <data key="virtual">True</data>
      <data key="is_a">sequence variant</data>
      <data key="properties">{'source': 'str', 'original_source': 'str', 'effect': 'str', 'biotype': 'str'}</data>
    </node>
    <node id="Intact.snRNASequence">
      <data key="label">intact.snRNA sequence</data>
      <data key="user_extension">True</data>
      <data key="preferred_id">intact</data>
      <data key="input_label">intact_snrna</data>
      <data key="represented_as">node</data>
      <data key="virtual">True</data>
      <data key="is_a">['snRNA sequence', 'nucleic acid entity']</data>
      <data key="properties">{'ac': 'str', 'fullName': 'str', 'shortName': 'str', 'preferredName': 'str'}</data>
      <data key="exclude_properties">sequence</data>
    </node>
    <node id="Rnacentral.snRNASequence">
      <data key="label">rnacentral.snRNA sequence</data>
      <data key="user_extension">True</data>
      <data key="preferred_id">rnacentral</data>
      <data key="input_label">rnacentral_snrna</data>
      <data key="represented_as">node</data>
      <data key="virtual">True</data>
      <data key="is_a">['snRNA sequence', 'nucleic acid entity']</data>
      <data key="properties">{'ac': 'str', 'fullName': 'str', 'shortName': 'str', 'preferredName': 'str'}</data>
      <data key="exclude_properties">sequence</data>
    </node>
    <node id="Intact.dsDNASequence">
      <data key="label">intact.dsDNA sequence</data>
      <data key="user_extension">True</data>
      <data key="preferred_id">intact</data>
      <data key="input_label">intact_dsdna</data>
      <data key="represented_as">node</data>
      <data key="virtual">True</data>
      <data key="is_a">['dsDNA sequence', 'DNA sequence', 'nucleic acid entity']</data>
      <data key="inherit_properties">True</data>
      <data key="properties">{'ac': 'str', 'fullName': 'str', 'shortName': 'str', 'preferredName': 'str', 'sequence': 'str'}</data>
      <data key="exclude_properties">{}</data>
    </node>
    <node id="Uniparc.dsDNASequence">
      <data key="label">uniparc.dsDNA sequence</data>
      <data key="user_extension">True</data>
      <data key="preferred_id">uniparc</data>
      <data key="input_label">uniprot_archive_dsdna</data>
      <data key="represented_as">node</data>
      <data key="virtual">True</data>
      <data key="is_a">['dsDNA sequence', 'DNA sequence', 'nucleic acid entity']</data>
      <data key="inherit_properties">True</data>
      <data key="properties">{'ac': 'str', 'fullName': 'str', 'shortName': 'str', 'preferredName': 'str', 'sequence': 'str'}</data>
      <data key="exclude_properties">{}</data>
    </node>
    <node id="Known.sequenceVariant.variantToGeneAssociation">
      <data key="label">known.sequence variant.variant to gene association</data>
      <data key="user_extension">True</data>
      <data key="source">known.sequence variant</data>
      <data key="input_label">VARIANT_FOUND_IN_GENE_Known_variant_Gene</data>
      <data key="represented_as">edge</data>
      <data key="virtual">True</data>
      <data key="is_a">variant to gene association</data>
      <data key="target">gene</data>
      <data key="preferred_id">id</data>
    </node>
    <node id="Somatic.sequenceVariant.variantToGeneAssociation">
      <data key="label">somatic.sequence variant.variant to gene association</data>
      <data key="user_extension">True</data>
      <data key="source">somatic.sequence variant</data>
      <data key="input_label">VARIANT_FOUND_IN_GENE_Somatic_mutation_Gene</data>
      <data key="represented_as">edge</data>
      <data key="virtual">True</data>
      <data key="is_a">variant to gene association</data>
      <data key="target">gene</data>
      <data key="preferred_id">id</data>
    </node>
    <edge source="Association" target="Entity" />
    <edge source="BehaviorToBehavioralFeatureAssociation" target="Association" />
    <edge source="BehaviorToBehavioralFeatureAssociation" target="EntityToPhenotypicFeatureAssociationMixin" />
    <edge source="EntityToPhenotypicFeatureAssociationMixin" target="EntityToFeatureOrDiseaseQualifiersMixin" />
    <edge source="EntityToPhenotypicFeatureAssociationMixin" target="FrequencyQuantifier" />
    <edge source="EntityToFeatureOrDiseaseQualifiersMixin" target="FrequencyQualifierMixin" />
    <edge source="FrequencyQuantifier" target="RelationshipQuantifier" />
    <edge source="CaseToPhenotypicFeatureAssociation" target="Association" />
    <edge source="CaseToPhenotypicFeatureAssociation" target="CaseToEntityAssociationMixin" />
    <edge source="ChemicalAffectsGeneAssociation" target="Association" />
    <edge source="ChemicalEntityAssessesNamedThingAssociation" target="Association" />
    <edge source="ChemicalEntityOrGeneOrGeneProductRegulatesGeneAssociation" target="Association" />
    <edge source="ChemicalGeneInteractionAssociation" target="Association" />
    <edge source="ChemicalGeneInteractionAssociation" target="ChemicalToEntityAssociationMixin" />
    <edge source="ChemicalToEntityAssociationMixin" target="ChemicalEntityToEntityAssociationMixin" />
    <edge source="ChemicalToDiseaseOrPhenotypicFeatureAssociation" target="Association" />
    <edge source="ChemicalToDiseaseOrPhenotypicFeatureAssociation" target="EntityToDiseaseOrPhenotypicFeatureAssociationMixin" />
    <edge source="ChemicalToPathwayAssociation" target="Association" />
    <edge source="ContributorAssociation" target="Association" />
    <edge source="DiseaseOrPhenotypicFeatureToGeneticInheritanceAssociation" target="Association" />
    <edge source="DiseaseOrPhenotypicFeatureToGeneticInheritanceAssociation" target="DiseaseOrPhenotypicFeatureToEntityAssociationMixin" />
    <edge source="DiseaseOrPhenotypicFeatureToLocationAssociation" target="Association" />
    <edge source="DiseaseToExposureEventAssociation" target="Association" />
    <edge source="DiseaseToExposureEventAssociation" target="DiseaseToEntityAssociationMixin" />
    <edge source="DiseaseToExposureEventAssociation" target="EntityToExposureEventAssociationMixin" />
    <edge source="DiseaseToPhenotypicFeatureAssociation" target="Association" />
    <edge source="DrugToGeneAssociation" target="Association" />
    <edge source="DrugToGeneAssociation" target="DrugToEntityAssociationMixin" />
    <edge source="EntityToDiseaseAssociation" target="Association" />
    <edge source="EntityToPhenotypicFeatureAssociation" target="Association" />
    <edge source="ExposureEventToOutcomeAssociation" target="Association" />
    <edge source="ExposureEventToOutcomeAssociation" target="EntityToOutcomeAssociationMixin" />
    <edge source="ExposureEventToPhenotypicFeatureAssociation" target="Association" />
    <edge source="GeneToExpressionSiteAssociation" target="Association" />
    <edge source="GeneToGeneFamilyAssociation" target="Association" />
    <edge source="GeneToPathwayAssociation" target="Association" />
    <edge source="GeneToPathwayAssociation" target="GeneToEntityAssociationMixin" />
    <edge source="GeneToPhenotypicFeatureAssociation" target="Association" />
    <edge source="GenotypeToGeneAssociation" target="Association" />
    <edge source="GenotypeToGenotypePartAssociation" target="Association" />
    <edge source="GenotypeToPhenotypicFeatureAssociation" target="Association" />
    <edge source="GenotypeToPhenotypicFeatureAssociation" target="GenotypeToEntityAssociationMixin" />
    <edge source="GenotypeToVariantAssociation" target="Association" />
    <edge source="InformationContentEntityToNamedThingAssociation" target="Association" />
    <edge source="MaterialSampleDerivationAssociation" target="Association" />
    <edge source="MaterialSampleToDiseaseOrPhenotypicFeatureAssociation" target="Association" />
    <edge source="MaterialSampleToDiseaseOrPhenotypicFeatureAssociation" target="MaterialSampleToEntityAssociationMixin" />
    <edge source="MolecularActivityToChemicalEntityAssociation" target="Association" />
    <edge source="MolecularActivityToMolecularActivityAssociation" target="Association" />
    <edge source="MolecularActivityToPathwayAssociation" target="Association" />
    <edge source="NamedThingAssociatedWithLikelihoodOfNamedThingAssociation" target="Association" />
    <edge source="OrganismTaxonToEnvironmentAssociation" target="Association" />
    <edge source="OrganismTaxonToEnvironmentAssociation" target="OrganismTaxonToEntityAssociation" />
    <edge source="OrganismToOrganismAssociation" target="Association" />
    <edge source="OrganismalEntityAsAModelOfDiseaseAssociation" target="Association" />
    <edge source="OrganismalEntityAsAModelOfDiseaseAssociation" target="EntityToDiseaseAssociationMixin" />
    <edge source="OrganismalEntityAsAModelOfDiseaseAssociation" target="ModelToDiseaseAssociationMixin" />
    <edge source="PopulationToPopulationAssociation" target="Association" />
    <edge source="SequenceVariantModulatesTreatmentAssociation" target="Association" />
    <edge source="TaxonToTaxonAssociation" target="Association" />
    <edge source="VariantToPhenotypicFeatureAssociation" target="Association" />
    <edge source="VariantToPhenotypicFeatureAssociation" target="VariantToEntityAssociationMixin" />
    <edge source="VariantToPopulationAssociation" target="Association" />
    <edge source="CellLineToDiseaseOrPhenotypicFeatureAssociation" target="Association" />
    <edge source="CellLineToDiseaseOrPhenotypicFeatureAssociation" target="CellLineToEntityAssociationMixin" />
    <edge source="CellLineAsAModelOfDiseaseAssociation" target="CellLineToDiseaseOrPhenotypicFeatureAssociation" />
    <edge source="ChemicalOrDrugOrTreatmentToDiseaseOrPhenotypicFeatureAssociation" target="Association" />
    <edge source="ChemicalOrDrugOrTreatmentSideEffectDiseaseOrPhenotypicFeatureAssociation" target="ChemicalOrDrugOrTreatmentToDiseaseOrPhenotypicFeatureAssociation" />
    <edge source="GenotypeToDiseaseAssociation" target="Association" />
    <edge source="GenotypeAsAModelOfDiseaseAssociation" target="GenotypeToDiseaseAssociation" />
    <edge source="SequenceAssociation" target="Association" />
    <edge source="GenomicSequenceLocalization" target="SequenceAssociation" />
    <edge source="VariantToDiseaseAssociation" target="Association" />
    <edge source="VariantAsAModelOfDiseaseAssociation" target="VariantToDiseaseAssociation" />
    <edge source="VariantToGeneAssociation" target="Association" />
    <edge source="VariantToGeneExpressionAssociation" target="VariantToGeneAssociation" />
    <edge source="VariantToGeneExpressionAssociation" target="GeneExpressionMixin" />
    <edge source="AnatomicalEntityToAnatomicalEntityAssociation" target="Association" />
    <edge source="AnatomicalEntityToAnatomicalEntityOntogenicAssociation" target="AnatomicalEntityToAnatomicalEntityAssociation" />
    <edge source="AnatomicalEntityToAnatomicalEntityPartOfAssociation" target="AnatomicalEntityToAnatomicalEntityAssociation" />
    <edge source="ChemicalToChemicalAssociation" target="Association" />
    <edge source="ChemicalToChemicalDerivationAssociation" target="ChemicalToChemicalAssociation" />
    <edge source="ReactionToParticipantAssociation" target="ChemicalToChemicalAssociation" />
    <edge source="ReactionToCatalystAssociation" target="ReactionToParticipantAssociation" />
    <edge source="OrganismTaxonToOrganismTaxonAssociation" target="Association" />
    <edge source="OrganismTaxonToOrganismTaxonInteraction" target="OrganismTaxonToOrganismTaxonAssociation" />
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