selection

Wright-Fisher population dynamics

Wright-Fisher model

There are N individuals in the population. Every generation, each individual has a Poisson number of offspring (looking forwards in time), or picks one random parent individual (looking backwards time). Generations are discrete and non-overlapping.

• Visualization of Wright-Fisher ancestry
• Visualization of Wright-Fisher haplotype dynamics

Wright-Fisher model with mutation and genetic drift

• iPython notebook

• Exercise on the effects of population size and mutation rate on population dynamics

• Neutral expectations for population summary statistics

Wright-Fisher model with mutation, genetic drift and selection

• iPython notebook

• Exercise on the effects of positive and negative selection on population dynamics

• Population summary statistics with selection

Conclusions on effects of selection and how to detect them

• Tests of selection