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[Feature Request] Incorporate/generalize reference genomes #5

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xonq opened this issue Jan 15, 2025 · 0 comments
Open

[Feature Request] Incorporate/generalize reference genomes #5

xonq opened this issue Jan 15, 2025 · 0 comments

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@xonq
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xonq commented Jan 15, 2025

These workflow wrappers currently only reference Candidozyma auris B11205 (GCA_016772135).

  • the WDL wrappers (task_mycosnp_variants.wdl and task_mycosnp_tree.wdl) are equipped with input variables that accommodate new organisms.
  • /reference/ in the quay.io/theiagen/mycosnp container contains the reference accession, and may need to be populated with new reference fasta, bwa, masked assembly, etc. as required by mycosnp-nf; alternatively, reference data can be generalized to gather on the fly by downloading an assembly for a source accession/biosample
  • task inputs need to be exposed to their associated workflows:
  String strain = "B11205"
  String accession = "GCA_016772135"
  • further modification to reference sequences is necessary to accommodate other lineages
@xonq xonq changed the title [Feature Request] Incorporate/generalize reference organisms [Feature Request] Incorporate/generalize reference genomes Jan 15, 2025
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