diff --git a/pyproject.toml b/pyproject.toml
index b9ac9346..5aabe77c 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -16,6 +16,21 @@ readme = {file = "README.md", content-type="text/markdown"}
 dynamic = ["version"]
 
 
-[project.urls]
-Source = "https://github.com/Intron7/rapids_singlecell"
+dependencies = [
+    "anndata>=0.7.4",
+    "numpy>=1.17.0",
+    "decoupler>=1.3.2",
+    "scipy>=1.4",
+    "pandas>=1.0",
+    "natsort",
+    "scikit-misc>=0.1.3",
+    "matplotlib>=3.4",
+    "seaborn",
+    "tqdm"
+]
 
+[project.optional-dependencies]
+rapids = ["cudf-cu11", "cuml-cu11", "cugraph-cu11"] 
+
+[project.urls]
+Source = "https://github.com/Intron7/rapids-singlecell"