KP.2.2 with ORF1a:K2017R (nsp3_K1199R), ORF1b:P970L (nsp13_P47L), and S:T22N (8 seqs, 4 countries including Lebanon) with 3 samples carrying 478T

[NkRMnZr]

Defining Mutations: KP.2.2 > A6315G(ORF1a:K2017R) > C16376T(ORF1b:P970L), C19164T, C21627A(S:T22N)
Query: A6315G, C21627A
Earliest seq: 24-08-06 (EPI_ISL_19339128, GBW sample ex. Lebanon; EPI_ISL_19344505 from Arizona the same day)
Latest seq: 24-09-02 (EPI_ISL_19419846, New York)
Sampled Countries: USA: 6 (TX/3; AZ; NY; GBW ex. Lebanon), Denmark (1)

Genomes:

for lineages.csv commit:

Denmark/DCGC-688529/2024
USA/AZ-ASPHL-1514/2024
USA/NY-CDC-LC1119646/2024
USA/NY-GBW-GKISBBBC42930/2024
USA/TX-HMH-M-145338/2024
USA/TX-HMH-M-145398/2024
USA/TX-HMH-M-145444/2024

epi_isl accessions:
EPI_ISL_19339128, EPI_ISL_19344505, EPI_ISL_19405796, EPI_ISL_19419846, EPI_ISL_19425951, EPI_ISL_19426039, EPI_ISL_19426076

UShER:
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_22772_e9ee00.json?label=id:node_7104267

Trivia:

• Already with further spike mutations like T478X (query : A29257G,C16376T) and A475V (Query:A3069C, T7922G ,C1473T)

[FedeGueli]

convergent with cov-lineages/pango-designation#2748

[FedeGueli]

I think this was highlighted by @aviczhl2 in the group i misread it as the other bigger lineages.

[FedeGueli]

I ve added the queries for the sublineages of interest

[FedeGueli]

8, France this last sample has 478T so i would track it with the query A29257G,C16376T