diff --git a/clippy_lints/src/transmute/missing_transmute_annotations.rs b/clippy_lints/src/transmute/missing_transmute_annotations.rs
index 08f36a2ed5d2..f36d45baa7fa 100644
--- a/clippy_lints/src/transmute/missing_transmute_annotations.rs
+++ b/clippy_lints/src/transmute/missing_transmute_annotations.rs
@@ -1,8 +1,8 @@
-use clippy_utils::diagnostics::span_lint_and_sugg;
+use clippy_utils::diagnostics::span_lint_and_then;
 use rustc_errors::Applicability;
 use rustc_hir::{GenericArg, HirId, LetStmt, Node, Path, TyKind};
 use rustc_lint::LateContext;
-use rustc_middle::ty::Ty;
+use rustc_middle::ty::{self, Ty};
 
 use crate::transmute::MISSING_TRANSMUTE_ANNOTATIONS;
 
@@ -68,14 +68,40 @@ pub(super) fn check<'tcx>(
     } else if is_function_block(cx, expr_hir_id) {
         return false;
     }
-    span_lint_and_sugg(
+    let span = last.ident.span.with_hi(path.span.hi());
+    span_lint_and_then(
         cx,
         MISSING_TRANSMUTE_ANNOTATIONS,
-        last.ident.span.with_hi(path.span.hi()),
+        span,
         "transmute used without annotations",
-        "consider adding missing annotations",
-        format!("{}::<{from_ty}, {to_ty}>", last.ident),
-        Applicability::MaybeIncorrect,
+        |diag| {
+            let from_ty_no_name = ty_cannot_be_named(from_ty);
+            let to_ty_no_name = ty_cannot_be_named(to_ty);
+            if from_ty_no_name || to_ty_no_name {
+                let to_name = match (from_ty_no_name, to_ty_no_name) {
+                    (true, false) => "origin type",
+                    (false, true) => "destination type",
+                    _ => "source and destination types",
+                };
+                diag.help(format!(
+                    "consider giving the {to_name} a name, and adding missing type annotations"
+                ));
+            } else {
+                diag.span_suggestion(
+                    span,
+                    "consider adding missing annotations",
+                    format!("{}::<{from_ty}, {to_ty}>", last.ident),
+                    Applicability::MaybeIncorrect,
+                );
+            }
+        },
     );
     true
 }
+
+fn ty_cannot_be_named(ty: Ty<'_>) -> bool {
+    matches!(
+        ty.kind(),
+        ty::Alias(ty::AliasTyKind::Opaque | ty::AliasTyKind::Inherent, _)
+    )
+}
diff --git a/tests/ui/missing_transmute_annotations_unfixable.rs b/tests/ui/missing_transmute_annotations_unfixable.rs
new file mode 100644
index 000000000000..08ba3b791ee7
--- /dev/null
+++ b/tests/ui/missing_transmute_annotations_unfixable.rs
@@ -0,0 +1,29 @@
+//@no-rustfix
+
+fn issue14984() {
+    async fn e() {}
+    async fn x() -> u32 {
+        0
+    }
+    async fn y() -> f32 {
+        0.0
+    };
+    let mut yy = unsafe { std::ptr::read(&y()) };
+    yy = unsafe { std::mem::transmute(std::ptr::read(&x())) };
+    //~^ missing_transmute_annotations
+
+    let mut zz = 0u8;
+    zz = unsafe { std::mem::transmute(std::ptr::read(&x())) };
+    //~^ missing_transmute_annotations
+
+    yy = unsafe { std::mem::transmute(zz) };
+    //~^ missing_transmute_annotations
+
+    fn a() -> impl Sized {
+        0u32
+    }
+
+    let mut b: f32 = 0.0;
+    b = unsafe { std::mem::transmute(a()) };
+    //~^ missing_transmute_annotations
+}
diff --git a/tests/ui/missing_transmute_annotations_unfixable.stderr b/tests/ui/missing_transmute_annotations_unfixable.stderr
new file mode 100644
index 000000000000..3d9a3daf51a7
--- /dev/null
+++ b/tests/ui/missing_transmute_annotations_unfixable.stderr
@@ -0,0 +1,36 @@
+error: transmute used without annotations
+  --> tests/ui/missing_transmute_annotations_unfixable.rs:12:29
+   |
+LL |     yy = unsafe { std::mem::transmute(std::ptr::read(&x())) };
+   |                             ^^^^^^^^^
+   |
+   = help: consider giving the source and destination types a name, and adding missing type annotations
+   = note: `-D clippy::missing-transmute-annotations` implied by `-D warnings`
+   = help: to override `-D warnings` add `#[allow(clippy::missing_transmute_annotations)]`
+
+error: transmute used without annotations
+  --> tests/ui/missing_transmute_annotations_unfixable.rs:16:29
+   |
+LL |     zz = unsafe { std::mem::transmute(std::ptr::read(&x())) };
+   |                             ^^^^^^^^^
+   |
+   = help: consider giving the origin type a name, and adding missing type annotations
+
+error: transmute used without annotations
+  --> tests/ui/missing_transmute_annotations_unfixable.rs:19:29
+   |
+LL |     yy = unsafe { std::mem::transmute(zz) };
+   |                             ^^^^^^^^^
+   |
+   = help: consider giving the destination type a name, and adding missing type annotations
+
+error: transmute used without annotations
+  --> tests/ui/missing_transmute_annotations_unfixable.rs:27:28
+   |
+LL |     b = unsafe { std::mem::transmute(a()) };
+   |                            ^^^^^^^^^
+   |
+   = help: consider giving the origin type a name, and adding missing type annotations
+
+error: aborting due to 4 previous errors
+