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Thanks for the feedback. I can surely do a patch for our cls file we have included.
However, I am wondering if this template function is still relevant as it seems Bioinformatics Journal (https://academic.oup.com/bioinformatics) is no more using this CLS class
Alternatively, you may prepare your manuscript in LaTeX, and then submit the source files directly as part of your submission. Please note that initial submissions are not required to follow the Word or LaTex template. However, because manuscripts are published online following acceptance , it is important that any revised version of the manuscript supplied by the author follow the provided templates. The Word* and LaTex* templates can be found here.
As described in this posting
https://tex.stackexchange.com/questions/453542/unable-to-use-texit-in-caption
bioinfo.cls defines an invalid font:
resulting in \textit not working in figure captions
xfun::session_info('rticles')
bioinfo-cap-it.Rmd.gz
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