diff --git a/Dockerfile b/Dockerfile
index 06dad8a..54b7b0a 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -1,19 +1,17 @@
 # This file is part of REANA.
-# Copyright (C) 2018, 2019, 2020, 2021, 2022, 2023 CERN.
+# Copyright (C) 2018, 2019, 2020, 2021, 2022, 2023, 2024 CERN.
 #
 # REANA is free software; you can redistribute it and/or modify it
 # under the terms of the MIT License; see LICENSE file for more details.
 
 # Use Ubuntu LTS base image
-FROM docker.io/library/ubuntu:20.04
+FROM docker.io/library/ubuntu:24.04
 
 # Use default answers in installation commands
 ENV DEBIAN_FRONTEND=noninteractive
 
-# Use distutils provided by the standard Python library instead of the vendored one in
-# setuptools, so that editable installations are stored in the right directory.
-# See https://github.com/pypa/setuptools/issues/3301
-ENV SETUPTOOLS_USE_DISTUTILS=stdlib
+# Allow pip to install packages in the system site-packages dir
+ENV PIP_BREAK_SYSTEM_PACKAGES=true
 
 # Prepare list of Python dependencies
 COPY requirements.txt /code/
@@ -23,16 +21,16 @@ COPY requirements.txt /code/
 RUN apt-get update -y && \
     apt-get install --no-install-recommends -y \
         gcc \
-        python3.8 \
-        python3-dev \
+        python3.12 \
+        python3.12-dev \
         python3-pip \
         vim-tiny && \
-    pip install --no-cache-dir --upgrade pip setuptools && \
+    pip install --no-cache-dir --upgrade setuptools && \
     pip install --no-cache-dir -r /code/requirements.txt && \
     apt-get remove -y \
         gcc \
-        python3-dev && \
-    apt-get autoremove -y &&  \
+        python3.12-dev && \
+    apt-get autoremove -y && \
     apt-get clean && \
     rm -rf /var/lib/apt/lists/*
 
@@ -63,7 +61,7 @@ ENV TERM=xterm \
 
 # Set image labels
 LABEL org.opencontainers.image.authors="team@reanahub.io"
-LABEL org.opencontainers.image.created="2024-03-04"
+LABEL org.opencontainers.image.created="2024-07-04"
 LABEL org.opencontainers.image.description="REANA reproducible analysis platform - Serial workflow engine component"
 LABEL org.opencontainers.image.documentation="https://reana-workflow-engine-serial.readthedocs.io/"
 LABEL org.opencontainers.image.licenses="MIT"
diff --git a/requirements.txt b/requirements.txt
index 2dd2aca..97dc2de 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -7,11 +7,11 @@
 amqp==5.2.0               # via kombu
 appdirs==1.4.4            # via fs
 attrs==23.2.0             # via jsonschema
-backports-zoneinfo[tzdata]==0.2.1  # via backports-zoneinfo, kombu
+backports.zoneinfo[tzdata]==0.2.1;python_version<"3.9" # via backports-zoneinfo, kombu
 bracex==2.4               # via wcmatch
 bravado==10.3.2           # via reana-commons
 bravado-core==6.1.0       # via bravado, reana-commons
-certifi==2024.2.2         # via requests
+certifi==2024.6.2         # via requests
 charset-normalizer==3.3.2  # via requests
 checksumdir==1.1.9        # via reana-commons
 click==8.1.7              # via reana-commons