diff --git a/python/cudf/CMakeLists.txt b/python/cudf/CMakeLists.txt
index 2a17bc5dbb7..090e475471d 100644
--- a/python/cudf/CMakeLists.txt
+++ b/python/cudf/CMakeLists.txt
@@ -37,7 +37,3 @@ rapids_cython_init()
 
 add_subdirectory(cudf/_lib)
 add_subdirectory(udf_cpp)
-
-if(DEFINED cython_lib_dir)
-  rapids_cython_add_rpath_entries(TARGET cudf PATHS "${cython_lib_dir}")
-endif()
diff --git a/python/cudf_kafka/CMakeLists.txt b/python/cudf_kafka/CMakeLists.txt
index 3e12eb6aa41..13b859bc33b 100644
--- a/python/cudf_kafka/CMakeLists.txt
+++ b/python/cudf_kafka/CMakeLists.txt
@@ -35,7 +35,3 @@ include(rapids-cython-core)
 rapids_cython_init()
 
 add_subdirectory(cudf_kafka/_lib)
-
-if(DEFINED cython_lib_dir)
-  rapids_cython_add_rpath_entries(TARGET cudf_kafka PATHS "${cython_lib_dir}")
-endif()
diff --git a/python/pylibcudf/CMakeLists.txt b/python/pylibcudf/CMakeLists.txt
index fe6e73a3f14..153570a4a7e 100644
--- a/python/pylibcudf/CMakeLists.txt
+++ b/python/pylibcudf/CMakeLists.txt
@@ -37,7 +37,3 @@ include(rapids-cython-core)
 rapids_cython_init()
 
 add_subdirectory(pylibcudf)
-
-if(DEFINED cython_lib_dir)
-  rapids_cython_add_rpath_entries(TARGET cudf PATHS "${cython_lib_dir}")
-endif()