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DESCRIPTION
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DESCRIPTION
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Package: HiCAGE
Type: Package
Title: Hi-C Annotation and Graphics Ensemble
Version: 1.0.0
Authors@R: person("Michael", "Workman", email = "[email protected]",
role = c("aut", "cre"))
Maintainer: Michael Workman <[email protected]>
Description: This package takes chromsome conformation capture data as input
and annotates each genomic region with segmentation data from StateHub
(http://statehub.org/statehub/), for example. This data can then be
annotated with the nearest gene and using RNA-seq data, expression values
can be linked to each gene. Moreover, these data can be combined into a
circle plot with heatmaps showing average score of chromsome conformation
capture interaction between segmentation marks as well as average FPKM
values for genes in each type of interaction.
Depends: R (>= 3.4.1)
Imports: readr,
tidyr,
dplyr,
GenomicRanges,
biomaRt,
IRanges,
magrittr,
circlize,
shiny,
shinydashboard,
grDevices,
graphics,
utils,
stats,
plotrix,
UpSetR,
topGO,
org.Hs.eg.db,
org.Mm.eg.db
License: GPL (>= 3)
Encoding: UTF-8
LazyData: true
biocViews: GeneExpression, GenomeAnnotation, DNA3DStructure,
FunctionalPrediction, Visualization, GUI, ChIPSeq, HiC
RoxygenNote: 6.0.1
Suggests: knitr,
rmarkdown
VignetteBuilder: knitr