diff --git a/Lib/test/test_capi/test_opt.py b/Lib/test/test_capi/test_opt.py
index bf22ef2a5922e7..ab27b8797c4620 100644
--- a/Lib/test/test_capi/test_opt.py
+++ b/Lib/test/test_capi/test_opt.py
@@ -2290,6 +2290,24 @@ def testfunc(n):
         self.assertNotIn("_GUARD_TOS_INT", uops)
         self.assertNotIn("_GUARD_NOS_INT", uops)
 
+    def test_unary_negative_long_float_type(self):
+        def testfunc(n):
+            for _ in range(n):
+                a = 9397
+                f = 9397.0
+                x = -a + -a
+                y = -f + -f
+
+        testfunc(TIER2_THRESHOLD)
+
+        ex = get_first_executor(testfunc)
+        self.assertIsNotNone(ex)
+        uops = get_opnames(ex)
+
+        self.assertNotIn("_GUARD_TOS_INT", uops)
+        self.assertNotIn("_GUARD_NOS_INT", uops)
+        self.assertNotIn("_GUARD_TOS_FLOAT", uops)
+        self.assertNotIn("_GUARD_NOS_FLOAT", uops)
 
 def global_identity(x):
     return x
diff --git a/Misc/NEWS.d/next/Core_and_Builtins/2025-06-06-19-17-22.gh-issue-131798.XoV8Eb.rst b/Misc/NEWS.d/next/Core_and_Builtins/2025-06-06-19-17-22.gh-issue-131798.XoV8Eb.rst
new file mode 100644
index 00000000000000..6a9d9c683f9a8c
--- /dev/null
+++ b/Misc/NEWS.d/next/Core_and_Builtins/2025-06-06-19-17-22.gh-issue-131798.XoV8Eb.rst
@@ -0,0 +1 @@
+Optimize ``_UNARY_NEGATIVE`` in JIT-compiled code.
diff --git a/Python/optimizer_bytecodes.c b/Python/optimizer_bytecodes.c
index a9d5e92ca02a59..e7b849dea18afe 100644
--- a/Python/optimizer_bytecodes.c
+++ b/Python/optimizer_bytecodes.c
@@ -476,6 +476,16 @@ dummy_func(void) {
         }
     }
 
+    op(_UNARY_NEGATIVE, (value -- res)) {
+        PyTypeObject *type = sym_get_type(value);
+        if (type == &PyLong_Type || type == &PyFloat_Type) {
+            res = sym_new_type(ctx, type);
+        }
+        else {
+            res = sym_new_not_null(ctx);
+        }
+    }
+
     op(_COMPARE_OP, (left, right -- res)) {
         if (oparg & 16) {
             res = sym_new_type(ctx, &PyBool_Type);
diff --git a/Python/optimizer_cases.c.h b/Python/optimizer_cases.c.h
index 4780e492f61d74..b74f6c269cc097 100644
--- a/Python/optimizer_cases.c.h
+++ b/Python/optimizer_cases.c.h
@@ -142,8 +142,16 @@
         }
 
         case _UNARY_NEGATIVE: {
+            JitOptSymbol *value;
             JitOptSymbol *res;
-            res = sym_new_not_null(ctx);
+            value = stack_pointer[-1];
+            PyTypeObject *type = sym_get_type(value);
+            if (type == &PyLong_Type || type == &PyFloat_Type) {
+                res = sym_new_type(ctx, type);
+            }
+            else {
+                res = sym_new_not_null(ctx);
+            }
             stack_pointer[-1] = res;
             break;
         }