--- a/pulpcore/app/wsgi.py
+++ b/pulpcore/app/wsgi.py
@@ -8,6 +8,7 @@ https://docs.djangoproject.com/en/3.2/howto/deployment/wsgi/
 """
 
 from django.core.wsgi import get_wsgi_application
+from opentelemetry.instrumentation.wsgi import OpenTelemetryMiddleware
 
 from pulpcore.app.entrypoint import using_pulp_api_worker
 
@@ -15,6 +16,7 @@ if not using_pulp_api_worker.get(False):
     raise RuntimeError("This app must be executed using pulpcore-api entrypoint.")
 
 application = get_wsgi_application()
+application = OpenTelemetryMiddleware(application)
 
 # Disabling Storage metrics until we find a solution to resource usage.
 # https://github.com/pulp/pulpcore/issues/5468
diff --git a/pulpcore/content/__init__.py b/pulpcore/content/__init__.py
index 14c65ea81..8b24272d7 100644
--- a/pulpcore/content/__init__.py
+++ b/pulpcore/content/__init__.py
@@ -20,6 +20,7 @@ from django.db.utils import (  # noqa: E402: module level not at top of file
     DatabaseError,
 )
 
+from opentelemetry.instrumentation.aiohttp_server import middleware as instrumentation
 from pulpcore.app.apps import pulp_plugin_configs  # noqa: E402: module level not at top of file
 from pulpcore.app.models import ContentAppStatus  # noqa: E402: module level not at top of file
 
@@ -29,7 +30,7 @@ from .authentication import authenticate  # noqa: E402: module level not at top
 
 log = logging.getLogger(__name__)
 
-app = web.Application(middlewares=[authenticate])
+app = web.Application(middlewares=[authenticate, instrumentation])
 
 CONTENT_MODULE_NAME = "content"