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What is the optimal threshold value of joint density? #7

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yuGithuuub opened this issue Dec 19, 2020 · 3 comments
Open

What is the optimal threshold value of joint density? #7

yuGithuuub opened this issue Dec 19, 2020 · 3 comments

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@yuGithuuub
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Dear Nebulosa group:
Thanks for your wonderful work in single cell visualization!
I've found that for well expressed markers, there's great performance.
But for some obviously wrong combinations, it will show a bad result,because of the joint density value.
What is the best threshold? Can I adjust the maximum value manually?

Rplot1
Rplot2

@joseah
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joseah commented Dec 19, 2020

Hi @yuGithuuub, thanks for your observation.
Most densities are non-zero, resulting in low joint densities values when markers are not "co-expressed".
We are currently working on improving the visualization for this scenario.
Any recommendations or feedback are very well welcome.

@yuGithuuub
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Looking forward to the improved version!

@BioMedInvestorNL
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Hi. Do you have an update on this? On how to set thresholds for the joint densities?

best

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