diff --git a/src/runtime/mkpreempt.go b/src/runtime/mkpreempt.go
index 64e220772e1ba2..31b6f5cbac3ad1 100644
--- a/src/runtime/mkpreempt.go
+++ b/src/runtime/mkpreempt.go
@@ -244,6 +244,15 @@ func genAMD64() {
 
 	// TODO: MXCSR register?
 
+	// Apparently, the signal handling code path in darwin kernel leaves
+	// the upper bits of Y registers in a dirty state, which causes
+	// many SSE operations (128-bit and narrower) become much slower.
+	// Clear the upper bits to get to a clean state. See issue #37174.
+	// It is safe here as Go code don't use the upper bits of Y registers.
+	p("#ifdef GOOS_darwin")
+	p("VZEROUPPER")
+	p("#endif")
+
 	p("PUSHQ BP")
 	p("MOVQ SP, BP")
 	p("// Save flags before clobbering them")
diff --git a/src/runtime/preempt_amd64.s b/src/runtime/preempt_amd64.s
index d50c2f3a5169c8..0f2fd7d8dd4d5b 100644
--- a/src/runtime/preempt_amd64.s
+++ b/src/runtime/preempt_amd64.s
@@ -4,6 +4,9 @@
 #include "textflag.h"
 
 TEXT ·asyncPreempt(SB),NOSPLIT|NOFRAME,$0-0
+	#ifdef GOOS_darwin
+	VZEROUPPER
+	#endif
 	PUSHQ BP
 	MOVQ SP, BP
 	// Save flags before clobbering them