Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Basic Melting Temperature #1

Open
AHReccese opened this issue May 4, 2024 · 2 comments
Open

Basic Melting Temperature #1

AHReccese opened this issue May 4, 2024 · 2 comments
Assignees
Milestone

Comments

@AHReccese
Copy link
Member

AHReccese commented May 4, 2024

Description

  • Basic

http://biotools.nubic.northwestern.edu/OligoCalc.html

Steps/Code to Reproduce

Expected Behavior

Actual Behavior

Operating System

Python Version

OPR Version (Use : opr.__version__)

@AHReccese AHReccese self-assigned this Jun 25, 2024
@AHReccese AHReccese added this to the opr v0.1 milestone Jun 25, 2024
@sepandhaghighi sepandhaghighi changed the title Melting Temperature Basic Melting Temperature Sep 29, 2024
@sepandhaghighi
Copy link
Member

Reference:

  1. Marmur, J. and Doty, P. 1962 Determination of the base composition of deoxyribonucleic acid from its thermal denaturation temperature. J. Mol. Biol.5109–118

  2. Alejandro Panjkovich, Francisco Melo, Comparison of different melting temperature calculation methods for short DNA sequences, Bioinformatics, Volume 21, Issue 6, March 2005, Pages 711–722, https://doi.org/10.1093/bioinformatics/bti066

Formula:

$${T}_{m}=64.9+41.0\times \left(\frac{y\hbox{ G }+z\hbox{ C }-16.4}{w\hbox{ A }+x\hbox{ T }+y\hbox{ G }+z\hbox{ C }}\right)$$

@sepandhaghighi
Copy link
Member

@AHReccese
Feel free to begin this task.

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Projects
None yet
Development

No branches or pull requests

2 participants